En el citado ensayo, llamado Breast Cancer Prevention Trial, se encontró que las mujeres que recibían el fármaco presentaron menor incidencia de cáncer mamario, tanto invasivo como no invasivo. Dado que otros estudios también habían asociado el uso de tamoxifeno a un menor riesgo de enfermedad mamaria invasiva, investigadores de la Cancer Research Network (Estados Unidos) examinaron sus efectos sobre una muestra de 13.203 mujeres tratadas con tamoxifeno o placebo que habían sido incluidas en el citado estudio.
Los resultados muestran que el fármaco reduce el riesgo de enfermedad mamaria benigna adenosis, quistes, ectasia ductal, enfermedad fibroquística, hiperplasia y metaplasia- en un 28%. También redujo el riesgo de fibroadenoma y fibrosis, dos entidades que se diagnostican mediante biopsia. Las sometidas al tratamiento con el fármaco necesitaron un 29% menos biopsias que las que recibieron placebo.
Webs Relacionadas
Cancer Research Network
http://www.cancerresearchnetwork.org/
Journal of the National Cancer Institute
http://jncicancerspectrum.oupjournals.org/
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