Los autores, de la Erasmus University de Rotterdam (Países Bajos), estudiaron ratones y observaron que los roedores con un defecto en un gen implicado en la reparación del ADN envejecían prematuramente, desarrollando huesos más frágiles, infertilidad, piel grisácea y otros rasgos del envejecimiento.
Además, los ratones con un defecto adiciones en el gen, llamado XPD, mostraban experimentaban una aceleración del proceso de envejecimiento, así como una mayor sensibilidad al daño oxidativo en su ADN.
Desde hace tiempo se sospecha que el deterioro del ADN contribuye a envejecer, aunque el mecanismo exacto no está nada claro.
Según los investigadores holandeses, su estudio proporciona la primera indicación clara de que el daño en el ADN se halla en la raíz del envejecimiento.
Webs Relacionadas
Science
http://www.sciencemag.org/
Erasmus Universiteit Rotterdam
http://www.eur.nl/
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