En la reunión de las Sociedades Británicas de Endocrinología, un equipo del Christie Hospital de Manchester explicó que los fumadores presentan mayores niveles de factor de crecimiento similar a la insulina (IGF) que los no fumadores.
Los niveles elevados de esta proteína en sangre se han asociado, según los resultados de investigaciones anteriores, con el cáncer de mama y colorrectal.
Los autores del nuevo estudio investigaron las historias de tabaquismo de más de 400 individuos de 55 a 65 años participantes en un programa de cribado de cáncer colorrectal. Encontraron que el tabaquismo a largo plazo incrementa los niveles de IGF en sangre, de forma estadísticamente significativa y dependiente de la dosis, con diferencias de hasta un 25% entre fumadores y no fumadores.
Los autores especulan con que este incremento de los niveles de IGF puede promover el cáncer y proteger a las células tumorales frente al mecanismo de apoptosis que conllevaría su autodestrucción.
Webs Relacionadas
21st Joint Meeting of the British Endocrine Societies
http://www.endocrinology.org/
Christie Hospital
http://www.christie.nhs.uk/
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