Científicos de la Universidad de Sheffield (Reino Unido) han descubierto que los portadores de una variante del gen 5-HT2C son menos susceptibles a engordar tras iniciar tratamiento con antipsicóticos. Al cabo de 10 semanas de tratamiento, el 15% de los portadores de la variante genética habían aumentado de peso un 7%, en contraste con el 51% de los que no eran portadores. El gen citado regula un receptor de la serotonina.
Webs Relacionadas
The Lancet
http://www.thelancet.com/
University of Sheffield
http://www.shef.ac.uk/
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Publicado el 27 de junio de 2002
Antipsicóticos, aumento de peso y mutaciones genéticas
Antipsicóticos
El aumento de peso es efecto secundario de algunos fármacos antipsicóticos que se emplean como tratamiento de la esquizofrenia. Sin embargo, un nuevo trabajo publicado en "The Lancet" señala que un gen es el que determina qué pacientes aumentarán de peso como consecuencia de la medicación y cuáles no.
Fuente:
Científicos de la Universidad de Sheffield (Reino Unido) han descubierto que los portadores de una variante del gen 5-HT2C son menos susceptibles a engordar tras iniciar tratamiento con antipsicóticos. Al cabo de 10 semanas de tratamiento, el 15% de los portadores de la variante genética habían aumentado de peso un 7%, en contraste con el 51% de los que no eran portadores. El gen citado regula un receptor de la serotonina.
Webs Relacionadas
The Lancet
http://www.thelancet.com/
University of Sheffield
http://www.shef.ac.uk/