El estudio es el primero que ha evaluado un agente farmacológico de investigación contra el bacilo del carbunco en un ensayo clínico desde los ataques producidos en Estados Unidos en otoño de 2001.
El fármaco, llamado PAmAb, puede utilizarse con individuos con sospecha de probable exposición a esporas de Bacillus anthracis.
Un sola dosis protegió por completo a ratas y proporcionó un importante beneficio en términos de supervivencia en monos y conejos. Posteriormente se evaluó su seguridad en 105 voluntarios sanos, inyectando el fármaco a distintas dosis por vía intramuscular o en infusión. Los resultados muestran que el anticuerpo monoclonal es seguro y bien tolerado.
Webs Relacionadas
Clinical Infectious Diseases
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