Información imprescindible para el clínico que deberían conocer los consumidores | 18 JUL 17

Efectos cardiovasculares de la cocaína

La cocaína ejerce sus diversos efectos adversos, a menudo graves, a través de numerosas vías fisiopatológicas
Autor/a: Havakuk O, Rezkalla SH, Kloner RA J Am Coll Cardiol 2017;70:101–13
INDICE:  1. Página 1 | 2.  Referencias bilibiográficas
Referencias bilibiográficas

1. Gärtner G. Die Entdeckung der Lokalanästhesie. Vienna, Austria: Der neue Tag, 1919.

2. Cartmell LW, Aufderheide AC, Springfield A, Arriaza B. The frequency and antiquity of prehistoric coca-leaf-chewing practices in Northern Chile: radioimmunoassay of a cocaine metabolite in human-mummy hair. Lat Am Antiq 1991;2:260–8.

3. Freud S. A contribution to the knowledge of the effect of cocaine, Vienna Medical Weekly, January, 1885. In: Byck R, editor. Cocaine Papers. New York, NY: Stonehill Publishing Co., 1974.

4. Hammond WA. Coca: its preparations and their therapeutical qualities with some remarks on the so-called “cocaine habit.” In: Byck R, editor. Cocaine Papers. New York, NY, 1974:177–93.

5. Drugs, brains, and behavior: the science of addiction. National Institutes of Health, National Institute on Drug Abuse. 2014. National Institutes of Health Pub No. 14-5605. Available at: https:// www.drugabuse.gov/sites/default/files/soa_2014. pdf. Accessed May 10, 2017.

6. Wohler V. Fortsetzung der Untersuchungen über die Coca und das Cocaïn. Justus Liebigs Annalen der Chemie 1862;121:372–5.

7. Inaba T, Stewart DJ, Kalow W. Metabolism of cocaine in man. Clin Pharmacol Ther 1978;23: 547–52.

8. Ambre J, Fischman M, Ruo TI. Urinary excretion of ecgonine methyl ester, a major metabolite of cocaine in humans. J Anal Toxicol 1984;8:23–5.

9. Perez-Reyes M, Di Guiseppi S, Ondrusek G, Jeffcoat AR, Cook CE. Free-base cocaine smoking. Clin Pharmacol Ther 1982;32: 459–65.

10. Jufer RA, Wstadik A, Walsh SL, Levine BS, Cone EJ. Elimination of cocaine and metabolites in plasma, saliva, and urine following repeated oral administration to human volunteers. J Anal Toxicol 2000; 24:467–77.

11. Gay GR. Clinical management of acute and chronic cocaine poisoning. Ann Emerg Med 1982; 11:562–72.

12. Hawks RL, Kopin IJ, Colburn RW, Thoa NB. Norcocaine: a pharmacologically active metabolite of cocaine found in brain. Life Sci 1974; 15: 2189–95.

13. Jones SR, Garris PA, Wightman RM. Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens. J Pharmacol Exp Ther 1995; 274:396–403.

14. Venton BJ, Seipel AT, Phillips PE, et al. Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. J Neurosci 2006; 26:3206–9.

15. Egashira K, Morgan KG, Morgan JP. Effects of cocaine on excitation-contraction coupling of aortic smooth muscle from the ferret. J Clin Invest 1991; 87:1322–8.

16. Wilbert-Lampen U, Seliger C, Zilker T, Arendt RM. Cocaine increases the endothelial release of immunoreactive endothelin and its concentrations in human plasma and urine: reversal by coincubation with s-receptor antagonists. Circulation 1998; 98:385–90.

17. Havranek EP, Nademanee K, Grayburn PA, Eichhorn EJ. Endothelium-dependent vasorelaxation is impaired in cocaine arteriopathy. J Am Coll Cardiol 1996; 28:1168–74.

18. Mo W, Singh AK, Arruda JA, Dunea G. Role of nitric oxide in cocaine-induced acute hypertension. Am J Hypertens 1998; 11:708–14.

19. Perreault CL, Morgan KG, Morgan JP. Effects of cocaine on intracellular calcium handling in cardiac and vascular smooth muscle. NIDA Res Monogr 1991;108:139–53.

20. Su J, Li J, Li W, Altura B, Altura B. Cocaine induces apoptosis in primary cultured rat aortic vascular smooth muscle cells: possible relationship to aortic dissection, atherosclerosis, and hypertension. Int J Toxicol 2004; 23:233–7.

21. Ramondo AB, Mistrorigo F, Angelini A. Intimal hyperplasia and cystic medial necrosis as substrate of acute coronary syndrome in a cocaine abuser: an in vivo/ex vivo pathological correlation. Heart 2009; 95:82.

22. Wilmink TB, Quick CR, Day NE. The association between cigarette smoking and abdominal aortic aneurysms. J Vasc Surg 1999; 30:1099–105.

23. Lange RA, Cigarroa RG, Yancy CW Jr., et al. Cocaine-induced coronary-artery vasoconstriction.N Engl J Med 1989; 321:1557–62.

24. Rezkalla SH, Mazza JJ, Kloner RA, Tillema V, Chang SH. Effects of cocaine on human platelets in healthy subjects. Am J Cardiol 1993; 72:243–6.

25. Siegel AJ, Mendelson JH, Sholar MB, et al. Effect of cocaine usage on C-reactive protein, von Willebrand factor, and fibrinogen. Am J Cardiol 2002; 89:1133–5.

26. Moliterno DJ, Lange RA, Gerard RD, Willard JE, Lackner C, Hillis LD. Influence of intranasal cocaine on plasma constituents associated with endogenous thrombosis and thrombolysis. Am J Med 1994; 6:492–6.

27. Kolodgie FD, Virmani R, Cornhill JF, Herderick EE, Smialek J. Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. J Am Coll Cardiol 1991; 17:1553–60.

28. Lucena J, Blanco M, Jurado C, et al. Cocaine related sudden death: a prospective investigation in south-west Spain. Eur Heart J 2010; 31:318–29.

29. Steinhauer JR, Caulfield JB. Spontaneous coronary artery dissection associated with cocaine use: a case report and brief review. Cardiovasc Pathol 2001;10:141–5.

30. Isner JM, Estes NA III, Thompson PD, et al. Acute cardiac events temporally related to cocaine abuse. N Engl J Med 1986; 315:1438–43.

31. Remondino A, Kwon SH, Communal C, et al. b-Adrenergic receptor–stimulated apoptosis in cardiac myocytes is mediated by reactive oxygen species/c-Jun NH2-terminal kinase–dependent activation of the mitochondrial pathway. Circ Res 2003; 92:136–8.

32. Nahas GG, Trouvé R, Manger WM. Cocaine, catecholamines and cardiac toxicity. Acta Anaesthesiol Scand Suppl 1990; 94:77–81.

33. Billman GE, Hoskins RS. Cocaine-induced ventricular fibrillation: protection afforded by the calcium antagonist verapamil. FASEB J 1988; 2: 2990–5.

34. Shih RD, Hollander JE, Burstein JL, Nelson LS, Hoffman RS, Quick AM. Clinical safety of lidocaine in patients with cocaine-associated myocardial infarction. Ann Emerg Med 1995;26: 702–6.

35. Ferreira S, Crumb WJ Jr., Carlton CG, Clarkson CW. Effects of cocaine and its major metabolites on the HERG-encoded potassium channel. J Pharmacol Exp Ther 2001; 299:220–6.

36. O’Leary ME, Hancox JC. Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias. Br J Clin Pharmacol 2010;69:427–42.

37. Clarkson CW, Xu YQ, Chang C, Follmer CH. Analysis of the ionic basis for cocaine’s biphasic effect on action potential duration in guinea-pig ventricular myocytes. J Mol Cell Cardiol 1996; 28: 667–78.

38. Crandall CG, Vongpatanasin W, Victor RG. Mechanism of cocaine-induced hyperthermia in humans. Ann Intern Med 2002; 136:785–91.

39. Crumb WJ Jr., Clarkson CW. Characterization of cocaine-induced block of cardiac sodium channels. Biophys J 1990;57:589–99.

40. Hoffman RS. Treatment of patients with cocaine-induced arrhythmias: bringing the bench to the bedside. Br J Clin Pharmacol 2010; 69: 448–57.

41. El Mazloum R, Snenghi R, Zorzi A, et al. Out of-hospital cardiac arrest after acute cocaine intoxication associated with Brugada ECG patterns: insights into physiopathologic mechanisms and implications for therapy. Int J Cardiol 2015; 195:245–9.

42. Álvarez Díaz H, Mari_no Callejo AI, García Rodríguez JF, Rodríguez Pazos L, Gómez Buela I, Bermejo Barrera AM. ANCA-positive vasculitis induced by levamisole-adulterated cocaine and nephrotic syndrome: the kidney as an unusual target. Am J Case Rep 2013; 14:557–61.

43. Karch SB, Mari F, Bartolini V, Bertol E. Aminorex poisoning in cocaine abusers. Int J Cardiol 2012; 158:344–6.

44. Albuquerque ML, Kurth CD. Cocaine constricts immature cerebral arterioles by a local anesthetic mechanism. Eur J Pharmacol 1993; 249:215–20.

45. Volkow ND, Mullani N, Gould KL, Adler S, Krajewski K. Cerebral blood flow in chronic cocaine users: a study with positron emission tomography. Br J Psychiatry 1988; 152:641–8.

46. Vongpatanasin W, Mansour Y, Chavoshan B, Arbique D, Victor RG. Cocaine stimulates the human cardiovascular system via a central mechanism of action. Circulation 1999; 100:497–502.

47. Snyder SH. Nitric oxide: first in a new class of neurotransmitters. Science 1992; 257:494–6.

48. Itzhak Y. Nitric oxide (NO) synthase inhibitors abolish cocaine-induced toxicity in mice. Neuropharmacology 1993; 32:1069–70.

49. Fogo A, Superdock KR, Atkinson JB. Severe arteriosclerosis in the kidney of a cocaine addict. Am J Kidney Dis 1992; 20:513–5.

50. Kibayashi K, Mastri AR, Hirsch CS. Cocaine induced intracerebral hemorrhage: analysis of predisposing factors and mechanisms causing hemorrhagic strokes. Hum Pathol 1995; 26: 659–63.

51. Brecklin CS, Gopaniuk-Folga A, Kravetz T, et al. Prevalence of hypertension in chronic cocaine users. Am J Hypertens 1998; 11:1279–83.

52. Braun BL, Murray DM, Sidney S. Lifetime cocaine use and cardiovascular characteristics among young adults: the CARDIA study. Am J Public Health 1997;87:629–34.

53. Eagle KA, Isselbacher EM, DeSanctis RW, International Registry for Aortic Dissection (IRAD) Investigators. Cocaine-related aortic dissection in perspective. Circulation 2002; 105:1529–30.

54. Hsue PY, Salinas CL, Bolger AF, Benowitz NL, Waters DD. Acute aortic dissection related to crack cocaine. Circulation 2002; 105:1592–5.

55. Daniel JC, Huynh TT, Zhou W, et al. Acute aortic dissection associated with use of cocaine. J Vasc Surg 2007; 46:427–33.

56. Dabbouseh NM, Ardelt A. Cocaine mediated apoptosis of vascular cells as a mechanism for carotid artery dissection leading to ischemic stroke. Med Hypotheses 2011; 77:201–3.

57. Bigi MA, Aslani A, Mehrpour M. Effect of chronic cocaine abuse on the elastic properties of aorta. Echocardiography 2008; 25:308–11.

58. Hall WC, Talbert RL, Ereshefsky L. Cocaine abuse and its treatment. Pharmacotherapy 1990; 10:47–65.

59. Brody SL, Slovis CM, Wrenn KD. Cocaine related medical problems: consecutive series of 233 patients. Am J Med 1990; 88:325–31.

60. Mittleman MA, Mintzer D, Maclure M, Tofler GH, Sherwood JB, Muller JE. Triggering of myocardial infarction by cocaine. Circulation 1999; 99:2737–41.

61. Weber JE, Shofer FS, Larkin GL, Kalaria AS, Hollander JE. Validation of a brief observation period for patients with cocaine-associated chest pain. N Engl J Med 2003; 348:510–7.

62. Weber JE, Chudnofsky CR, Boczar M, Boyer EW, Wilkerson MD, Hollander JE. Cocaine associated chest pain: how common is myocardial infarction? Acad Emerg Med 2000; 7: 873–7.

63. Gitter MJ, Goldsmith SR, Dunbar DN, Sharkey SW. Cocaine and chest pain: clinical features and outcome of patients hospitalized to rule out myocardial infarction. Ann Intern Med 1991; 115:277–82.

64. Hollander JE, Levitt MA, Young GP, Briglia E, Wetli CV, Gawad Y. Effect of recent cocaine use on the specificity of cardiac markers for diagnosis of acute myocardial infarction. Am Heart J 1998; 135: 245–52.

65. Hollander JE, Hoffman RS, Gennis P, et al. Prospective multicenter evaluation of cocaine associated chest pain. Cocaine Associated Chest Pain (COCHPA) Study Group. Acad Emerg Med 1994; 1:330–9.

66. Rubin RB, Neugarten J. Cocaine-induced rhabdomyolysis masquerading as myocardial ischemia. Am J Med 1989; 86:551–3.

67. Tashkin DP, Khalsa ME, Gorelick D, et al. Pulmonary status of habitual cocaine smokers. Am Rev Respir Dis 1992;145:92–100.

68. Hollander JE, Hoffman RS, Burstein JL, Shih RD, Thode HC Jr. Cocaine-associated myocardial infarction. Mortality and complications. Arch Intern Med 1995; 155:1081–6.

69. Chase M, Brown AM, Robey JL, et al. Application of the TIMI risk score in ED patients with cocaine-associated chest pain. Am J Emerg Med 2007; 25:1015–8.

70. Anderson JL, Adams CD, Antman EM, et al. 2012 ACCF/AHA focused update incorporated into the ACCF/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2013; 61:e179–348.

71. Kontos MC, Schmidt KL, Nicholson CS, Ornato JP, Jesse RL, Tatum JL. Myocardial perfusion imaging with technetium-99m sestamibi in patients with cocaine-associated chest pain. Ann Emerg Med 1999;33:639–45.

72. Walsh K, Chang AM, Perrone J, et al. Coronary computerized tomography angiography for rapid discharge of low-risk patients with cocaine-associated chest pain. J Med Toxicol 2009;5: 111–9.

73. Brogan WC III, Lange RA, Kim AS, Moliterno DJ, Hillis LD. Alleviation of cocaine induced coronary vasoconstriction by nitroglycerin. J Am Coll Cardiol 1991; 18:581–6.

74. Negus BH, Willard JE, Hillis LD, et al. Alleviation of cocaine-induced coronary vasoconstriction with intravenous verapamil. Am J Cardiol 1994; 73: 510–3.

 

Comentarios

Para ver los comentarios de sus colegas o para expresar su opinión debe ingresar con su cuenta de IntraMed.

AAIP RNBD
Términos y condiciones de uso | Política de privacidad | Todos los derechos reservados | Copyright 1997-2024