Hemorragia intracerebral aguda | 20 AGO 12

Descenso temprano de la TA y mejor control del hematoma cerebral

En pacientes con hemorragia intracerebral, los que más se beneficiaron (menor crecimiento del hematoma), fueron aquellos que recibieron tratamiento antihipertensivo intensivo en forma precoz e intensiva. Con el comentario editorial del Dr. Ignacio Previgliano.
Autor/a: Dres. Arima H, Huang Y, Wang JG, Stroke 2012;43.
INDICE:  1. Artículo | 2. Comentario editorial: Dr. I. Previgliano | 3. Referencias artículo original
Referencias artículo original

Referencias
1. Brott T, Broderick J, Kothari R, Barsan W, Tomsick T, Sauerbeck L, et al. Early hemorrhage growth in patients with intracerebral hemorrhage. Stroke. 1997;28:1–5.
2. Davis SM, Broderick J, Hennerici M, Brun NC, Diringer MN, Mayer SA, et al. Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage. Neurology. 2006;66:1175–1181.
3. Delcourt C, Huang Y, Arima H, Chalmers J, Davis SM, Heeley EL, et al; for the INTERACT1 Investigators. Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study. Neurology. In press.
4. Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, et al; for the FAST trial investigators. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008;358:2127–2137.
5. Anderson CS, Huang Y, Wang JG, Arima H, Neal B, Peng B, et al; for the INTERACT Investigators. Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial. Lancet Neurol. 2008;7:391–399. 6.
6. Anderson CS, Huang Y, Arima H, Heeley E, Skulina C, Parsons MW, et al; for the INTERACT Investigators. Effects of early intensive blood pressure-lowering treatment on the growth of hematoma and perihematomal edema in acute intracerebral hemorrhage: the Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT). Stroke. 2010;41:307–312.
7. Kazui S, Naritomi H, Yamamoto H, Sawada T, Yamaguchi T. Enlargement of spontaneous intracerebral hemorrhage. Incidence and time course. Stroke. 1996;27:1783–1787.
8. Arima H, Wang JG, Huang Y, Heeley E, Skulina C, Parsons MW, et al; for the INTERACT Investigators. Significance of perihematomal edema in acute intracerebral hemorrhage: the INTERACT trial. Neurology. 2009;73:1963–1968.
9. Arima H, Anderson CS, Wang JG, Huang Y, Heeley E, Neal B, et al; for the INTERACT investigators. Lower treatment blood pressure is associated with greatest reduction in hematoma growth after acute intracerebral hemorrhage. Hypertension. 2010;56:852– 858.
10. Mayer SA, Davis SM, Skolnick BE, Brun NC, Begtrup K, Broderick JP, et al. Can a subset of intracerebral hemorrhage patients benefit from hemostatic therapy with recombinant activated Factor VII? Stroke. 2009; 40:833– 840.

 

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