Hechos y cifras | 02 AGO 21

Enfermedad por reflujo gastroesofágico en neonatos

Revisión sobre definición, epidemiología, fisiopatología y herramientas diagnósticas y terapéuticas de la enfermedad por reflujo gastroesofágico en neonatos
Autor/a: Jenny Bellodas Sanchez, Sudarshan R. Jadcherla  NeoReviews February 2021, 22 (2)
INDICE:  1. Texto principal | 2. Texto principal
Texto principal

1. López-Alonso M, Moya MJ, Cabo JA, et al. Twenty-four-hour esophageal impedance-pH monitoring in healthy preterm neonates: rate and characteristics of acid, weakly acidic, and weakly alkaline gastroesophageal reflux. Pediatrics. 2006;118(2):e299–e308

2. Gulati IK, Jadcherla SR. Gastroesophageal reflux disease in the neonatal intensive care unit infant: who needs to be treated and what approach is beneficial? Pediatr Clin North Am. 2019;66(2):461–473

3. Funderburk A, Nawab U, Abraham S, et al. Temporal association between reflux-like behaviors and gastroesophageal reflux in preterm and term infants. J Pediatr Gastroenterol Nutr. 2016;62(4):556–561

4. Malcolm WF, Cotten CM. Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates. Clin Perinatol. 2012;39(1):99–109

5. Guillet R, Stoll BJ, Cotten CM, et al; National Institute of Child Health and Human Development Neonatal Research Network. Association of H2-blocker therapy and higher incidence of necrotizing enterocolitis in very low birth weight infants. Pediatrics. 2006;117(2):e137–e142

6. Terrin G, Passariello A, De Curtis M, et al. Ranitidine is associated with infections, necrotizing enterocolitis, and fatal outcome in newborns. Pediatrics. 2012;129(1):e40–e45

7. Orenstein SR, Hassall E, Furmaga-Jablonska W, Atkinson S, Raanan M. Multicenter, double-blind, randomized, placebo-controlled trial assessing the efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease. J Pediatr. 2009;154(4):514–520.e4

8. Ho T, Dukhovny D, Zupancic JAF, Goldmann DA, Horbar JD, Pursley DM. Choosing wisely in newborn medicine: five opportunities to increase value. Pediatrics. 2015;136(2):e482–e489

9. Rosen R, Vandenplas Y, Singendonk M, et al. Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2018;66(3):516–554

10. Jadcherla SR, Slaughter JL, Stenger MR, Klebanoff M, Kelleher K, Gardner W. Practice variance, prevalence, and economic burden of premature infants diagnosed with GERD. Hosp Pediatr. 2013;3(4):335–341

11. Slaughter JL, Stenger MR, Reagan PB, Jadcherla SR. Neonatal histamine-2 receptor antagonist and proton pump inhibitor treatment at United States Children’s Hospitals. J Pediatr. 2016;174:63–70.e3

12. Goyal RK, Chaudhury A. Physiology of normal esophageal motility. J Clin Gastroenterol. 2008;42(5):610–619

13. Butin JW, Olsen AM, Moersch HJ, Code CF. A study of esophageal pressures in normal persons and patients with cardiospasm. Gastroenterology. 1968;54(4 suppl):773–775

14. Ingelfinger FJ, Kramer P, Sanchez GC. The gastroesophageal vestibule, its normal function and its role in cardiospasm and gastroesophageal reflux. Am J Med Sci. 1954;228(4):417–425

15. Pena EM, Parks VN, Peng J, et al. Lower esophageal sphincter relaxation reflex kinetics: effects of peristaltic reflexes and maturation in human premature neonates. Am J Physiol Gastrointest Liver Physiol. 2010;299(6):G1386–G1395

16. Mittal RK, Rochester DF, McCallum RW. Electrical and mechanical activity in the human lower esophageal sphincter during diaphragmatic contraction. J Clin Invest. 1988;81(4):1182–1189

17. Omari TI, Benninga MA, Barnett CP, Haslam RR, Davidson GP, Dent J. Characterization of esophageal body and lower esophageal sphincter motor function in the very premature neonate. J Pediatr. 1999;135(4):517–521

18. Nelson SP, Chen EH, Syniar GM, Christoffel KK; Pediatric Practice Research Group. Prevalence of symptoms of gastroesophageal reflux during infancy: a pediatric practice-based survey. Arch Pediatr Adolesc Med. 1997;151(6):569–572

19. Campanozzi A, Boccia G, Pensabene L, et al. Prevalence and natural history of gastroesophageal reflux: pediatric prospective survey. Pediatrics. 2009;123(3):779–783

20. Gupta A, Jadcherla SR. The relationship between somatic growth and in vivo esophageal segmental and sphincteric growth in human neonates. J Pediatr Gastroenterol Nutr. 2006;43(1):35–41

21. Omari TI, Miki K, Fraser R, et al. Esophageal body and lower esophageal sphincter function in healthy premature infants. Gastroenterology. 1995;109(6):1757–1764

22. Omari TI, Barnett CP, Benninga MA, et al. Mechanisms of gastrooesophageal reflux in preterm and term infants with reflux disease. Gut. 2002;51(4):475–479

23. Ewer AK, Durbin GM, Morgan ME, Booth IW. Gastric emptying and gastro-oesophageal reflux in preterm infants. Arch Dis Child Fetal Neonatal Ed. 1996;75(2):F117–F121

24. Gupta A, Gulati P, Kim W, Fernandez S, Shaker R, Jadcherla SR. Effect of postnatal maturation on the mechanisms of esophageal propulsion in preterm human neonates: primary and secondary peristalsis. Am J Gastroenterol. 2009;104(2):411–419

25. Werlin SL, Dodds WJ, Hogan WJ, Arndorfer RC. Mechanisms of gastroesophageal reflux in children. J Pediatr. 1980;97(2):244–249

26. Omari TI, Rommel N, Staunton E, et al. Paradoxical impact of body positioning on gastroesophageal reflux and gastric emptying in the premature neonate. J Pediatr. 2004;145(2):194–200

27. Wyman JB, Dent J, Heddle R, Dodds WJ, Toouli J, Downton J. Control of belching by the lower oesophageal sphincter. Gut. 1990;31(6):639–646

28. Sun M, Wang WL, Wang W, Wen DL, Zhang H, Han YK. Gastroesophageal manometry and 24-hour double pH monitoring in neonates with birth asphyxia. World J Gastroenterol. 2001;7(5):695–697

29. Pensabene L, Miele E, Del Giudice E, Strisciuglio C, Staiano A. Mechanisms of gastroesophageal reflux in children with sequelae of birth asphyxia. Brain Dev. 2008;30(9):563–571

30. Omari T, Barnett C, Snel A, et al. Mechanism of gastroesophageal reflux in premature infants with chronic lung disease. J Pediatr Surg. 1999;34(12):1795–1798

31. Martin RJ, Hibbs AM. Diagnosing gastroesophageal reflux in preterm infants. Pediatrics. 2006;118(2):793–794

32. Nobile S, Noviello C, Cobellis G, Carnielli VP. Are infants with bronchopulmonary dysplasia prone to gastroesophageal reflux? a prospective observational study with esophageal pH-impedance monitoring. J Pediatr. 2015;167(2):279–285 e1

33. Jadcherla SR, Peng J, Chan CY, et al. Significance of gastroesophageal refluxate in relation to physical, chemical, and spatiotemporal characteristics in symptomatic intensive care unit neonates. Pediatr Res. 2011;70(2):192–198

34. Jadcherla SR, Gupta A, Fernandez S, et al. Spatiotemporal characteristics of acid refluxate and relationship to symptoms in premature and term infants with chronic lung disease. Am J Gastroenterol. 2008;103(3):720–728

35. Hassall E. Over-prescription of acid-suppressing medications in infants: how it came about, why it’s wrong, and what to do about it. J Pediatr. 2012;160(2):193–198

36. Poets CF, Brockmann PE. Myth: gastroesophageal reflux is a pathological entity in the preterm infant. Semin Fetal Neonatal Med. 2011;16(5):259–263

37. Dhillon AS, Ewer AK. Diagnosis and management of gastrooesophageal reflux in preterm infants in neonatal intensive care units. Acta Paediatr. 2004;93(1):88–93

38. Leape LL, Holder TM, Franklin JD, Amoury RA, Ashcraft KW. Respiratory arrest in infants secondary to gastroesophageal reflux. Pediatrics. 1977;60(6):924–928

 

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