Estrategias que mejoran la salud cardiometabólica

1. Guariguata L, Whiting D, Hambleton I, Beagley J, Linnenkamp U, Shaw J. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract (2014) 103(2):137–49. doi:10.1016/j.diabres.2013.11.002

2. Laakso M. Hyperglycemia and cardiovascular disease in type 2 diabetes. Diabetes (1999) 48(5):937–42. doi:10.2337/diabetes.48.5.937

3. Fox CS, Coady S, Sorlie PD, D’Agostino RB, Pencina MJ, Vasan RS, et al. Increasing cardiovascular disease burden due to diabetes mellitus the Framingham Heart Study. Circulation (2007) 115(12):1544–50. doi:10.1161/CIRCULATIONAHA.106.658948

4. Haffner SM, Stern MP, Hazuda HP, Mitchell BD, Patterson JK. Cardiovascular risk factors in confirmed prediabetic individuals: does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA (1990) 263(21):2893–8. doi:10.1001/jama.263.21.2893

5. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med (1998) 15(7):539–53. doi:10.1002/(SICI)1096-9136(199807)15:7<539::AIDDIA668>3.0.CO;2-S

6. Warburton DE, Nicol CW, Bredin SS. Health benefits of physical activity: the evidence. Can Med Assoc J (2006) 174(6):801–9. doi:10.1503/cmaj.051351

7. Diabetes Prevention Program Research Group, Knowler WC, Fowler SE, Hamman RF, Christophi CA, Hoffman HJ, et al. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet (2009) 374(9702):1677–86. doi:10.1016/S0140-6736(09)61457-4

8. Wing R, Bolin P, Brancati F, Bray G, Clark J, Coday M, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med (2013) 369(2):145–54. doi:10.1056/NEJMoa1212914

9. Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, et al. Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care (2016) 39(11):2065–79.

10. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome. Circulation (2005) 112(17):2735–52. doi:10.1161/CIRCULATIONAHA.105.169405

11. Inzucchi SE, Bergenstal R, Buse JB, Diamant M, Ferrannini E, Nauck M, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia (2012) 55(6):1577–96. doi:10.1007/s00125-012-2534-0

12. Knowler WC, Barrett-Connor E, Fowler SE, Hamman RF, Lachin JM, Walker EA, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med (2002) 346: 393–403. doi:10.1056/NEJMoa012512

13. Jung ME, Bourne JE, Beauchamp MR, Robinson E, Little JP. High-intensity interval training as an efficacious alternative to moderate-intensity continuous training for adults with prediabetes. J Diabetes Res (2015) 2015:9.

14. Hu T, Yao L, Reynolds K, Niu T, Li S, Whelton P, et al. Adherence to lowcarbohydrate and low-fat diets in relation to weight loss and cardiovascular risk factors. Obes Sci Pract (2016) 2(1):24–31. doi:10.1002/osp4.23

15. Kennedy ET, Bowman SA, Powell R. Dietary-fat intake in the US population. J Am Coll Nutr (1999) 18(3):207–12. doi:10.1080/07315724.1999.10 718853

16. Mokdad AH, Bowman BA, Ford ES, Vinicor F, Marks JS, Koplan JP. The continuing epidemics of obesity and diabetes in the United States. JAMA (2001) 286(10):1195–200. doi:10.1001/jama.286.10.1195

17. Noakes TD, Windt J. Evidence that supports the prescription of lowcarbohydrate high-fat diets: a narrative review. Br J Sports Med (2017) 51(2): 133–9. doi:10.1136/bjsports-2016-096491

18. Coulston AM, Hollenbeck CB, Swislocki AL, Chen YI, Reaven GM. Deleterious metabolic effects of high-carbohydrate, sucrose-containing diets in patients with non-insulin-dependent diabetes mellitus. Am J Med (1987) 82(2):213–20. doi:10.1016/0002-9343(87)90058-1

19. Garg A, Grundy SM, Koffler M. Effect of high carbohydrate intake on hyperglycemia, islet function, and plasma lipoproteins in NIDDM. Diabetes Care (1992) 15(11):1572–80. doi:10.2337/diacare.15.11.1572

20. Reaven GM. The role of insulin resistance and hyperinsulinemia in coronary heart disease. Metabolism (1992) 41(5):16–9. doi:10.1016/0026- 0495(92)90088-R

21. American Diabetes Association. Nutrition recommendations and interventions for diabetes. Diabetes Care (2008) 31(Suppl 1):S61–78. doi:10.2337/dc08-S061

22. Samaha FF, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, et al. A low-carbohydrate as compared with a low-fat diet in severe obesity. N Engl J Med (2003) 348(21):2074–81. doi:10.1056/NEJMoa022637

23. Volek JS, Sharman MJ, Gómez AL, Judelson DA, Rubin MR, Watson G, et al. Comparison of energy-restricted very low-carbohydrate and low-fat diets on weight loss and body composition in overweight men and women. Nutr Metab (2004) 1(1):13. doi:10.1186/1743-7075-1-13

24. Forsythe CE, Phinney SD, Fernandez ML, Quann EE, Wood RJ, Bibus DM, et al. Comparison of low fat and low carbohydrate diets on circulating fatty acid composition and markers of inflammation. Lipids (2008) 43(1):65–77. doi:10.1007/s11745-007-3132-7

25. Westman EC, Yancy WS, Mavropoulos JC, Marquart M, McDuffie JR. The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus. Nutr Metab (2008) 5(1):36. doi:10.1186/1743-7075-5-36

26. Boden G, Sargrad K, Homko C, Mozzoli M, Stein TP. Effect of a lowcarbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes. Ann Intern Med (2005) 142(6):403–11. doi:10.7326/0003-4819-142-6-200503150-00006

27. Dyson P, Beatty S, Matthews D. A low-carbohydrate diet is more effective in reducing body weight than healthy eating in both diabetic and nondiabetic subjects. Diabet Med (2007) 24(12):1430–5. doi:10.1111/j.1464-5491. 2007.02290.x

28. Feinman RD, Pogozelski WK, Astrup A, Bernstein RK, Fine EJ, Westman EC, et al. Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base. Nutrition (2015) 31(1):1–13. doi:10.1016/j.nut.2014.06.011

29. Gannon MC, Nuttall FQ. Control of blood glucose in type 2 diabetes without weight loss by modification of diet composition. Nutr Metab (2006) 3(1):16. doi:10.1186/1743-7075-3-16

30. Nuttall FQ, Schweim K, Hoover H, Gannon MC. Effect of the LoBAG 30 diet on blood glucose control in people with type 2 diabetes. Br J Nutr (2008) 99(03):511–9. doi:10.1017/S0007114507819155

31. Accurso A, Bernstein RK, Dahlqvist A, Draznin B, Feinman RD, Fine EJ, et al. Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab (2008) 5(1):9. doi:10.1186/1743-7075-5-9

32. Paoli A, Rubini A, Volek J, Grimaldi K. Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets. Eur J Clin Nutr (2013) 67(8):789–96. doi:10.1038/ejcn.2013.116

33. Cornier MA, Donahoo WT, Pereira R, Gurevich I, Westergren R, Enerback S, et al. Insulin sensitivity determines the effectiveness of dietary macronutrient composition on weight loss in obese women. Obes Res (2005) 13(4):703–9. doi:10.1038/oby.2005.79

34. Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014. Atlanta, GA: US Department of Health and Human Services (2014).

35. Stern L, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, et al. The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med (2004) 140(10):778–85. doi:10.7326/0003-4819-140-10-200405180-00007

36. Meckling KA, O’Sullivan C, Saari D. Comparison of a low-fat diet to a low carbohydrate diet on weight loss, body composition, and risk factors for diabetes and cardiovascular disease in free-living, overweight men and women. J Clin Endocrinol Metab (2004) 89(6):2717–23. doi:10.1210/jc.2003-031606

37. Yancy WS, Westman EC, McDuffie JR, Grambow SC, Jeffreys AS, Bolton J, et al. A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight loss. Arch Intern Med (2010) 170(2):136–45. doi:10.1001/ archinternmed.2009.492

38. Bianchi C, Miccoli R, Penno G, Del Prato S. Primary prevention of cardiovascular disease in people with dysglycemia. Diabetes Care (2008) 31(Suppl 2):S208–14. doi:10.2337/dc08-s256.

39. Gannon MC, Hoover H, Nuttall FQ. Further decrease in glycated hemoglobin following ingestion of a LoBAG 30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetes. Nutr Metab (2010) 7(1):64. doi:10.1186/1743-7075-7-64

40. Nuttall FQ, Almokayyad RM, Gannon MC. Comparison of a carbohydrate free diet vs. fasting on plasma glucose, insulin and glucagon in type 2 diabetes. Metabolism (2015) 64(2):253–62. doi:10.1016/j.metabol.2014.10.004

41. Alarcon C, Boland BB, Uchizono Y, Moore PC, Peterson B, Rajan S, et al. Pancreatic β-cell adaptive plasticity in obesity increases insulin production but adversely affects secretory function. Diabetes (2016) 65(2):438–50. doi:10.2337/db15-0792

42. Little JP, Myette-Côté É. Comment on Alarcon et al. Pancreatic β-cell adaptive plasticity in obesity increases insulin production but adversely affects secretory function. Diabetes 2016; 65: 438–450. Diabetes (2016) 65(8):e28. doi:10.2337/db16-0492

43. Blair SN. Physical inactivity: the biggest public health problem of the 21^st century. Br J Sports Med (2009) 43(1):1–2.

44. Kohl HW, Craig CL, Lambert EV, Inoue S, Alkandari JR, Leetongin G, et al. The pandemic of physical inactivity: global action for public health. Lancet (2012) 380(9838):294–305. doi:10.1016/S0140-6736(12)60898-8

45. Hawley JA, Hargreaves M, Joyner MJ, Zierath JR. Integrative biology of exercise. Cell (2014) 159(4):738–49. doi:10.1016/j.cell.2014.10.029

46. Pedersen BK, Saltin B. Exercise as medicine-evidence for prescribing exercise as therapy in 26 different chronic diseases. Scand J Med Sci Sports (2015) 25(S3):1–72. doi:10.1111/sms.12581

47. Kaminsky LA, Arena R, Beckie TM, Brubaker PH, Church TS, Forman DE, et al. The importance of cardiorespiratory fitness in the United States: the need for a national registry. Circulation (2013) 127(5):652–62. doi:10.1161/ CIR.0b013e31827ee100

48. Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA (2009) 301(19): 2024–35. doi:10.1001/jama.2009.681

49. Lee D-C, Sui X, Artero EG, Lee I-M, Church TS, McAuley PA, et al. Longterm effects of changes in cardiorespiratory fitness and body mass index on all-cause and cardiovascular disease mortality in men. Circulation (2011) 124(23):2483–90. doi:10.1161/CIRCULATIONAHA.111.038422

50. Gormley SE, Swain DP, High R, Spina RJ, Dowling EA, Kotipalli US, et al. Effect of intensity of aerobic training on VO2max. Med Sci Sports Exerc (2008) 40(7):1336–43. doi:10.1249/01.mss.0000321629.41403.46

51. Ross R, de Lannoy L, Stotz PJ. Separate effects of intensity and amount of exercise on interindividual cardiorespiratory fitness response. Mayo Clin Proc (2015) 90:1506–14. doi:10.1016/j.mayocp.2015.07.024

52. Boulé NG, Haddad E, Kenny GP, Wells GA, Sigal RJ. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA (2001) 286(10):1218–27. doi:10.1001/jama.286.10.1218

53. Boulé N, Kenny G, Haddad E, Wells G, Sigal R. Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in type 2 diabetes mellitus. Diabetologia (2003) 46(8):1071–81. doi:10.1007/s00125-003-1160-2

54. Snowling NJ, Hopkins WG. Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients. Diabetes Care (2006) 29(11):2518–27. doi:10.2337/dc06-1317

55. Marwick TH, Hordern MD, Miller T, Chyun DA, Bertoni AG, Blumenthal RS, et al. Exercise training for type 2 diabetes mellitus. Circulation (2009) 119(25):3244–62. doi:10.1161/CIRCULATIONAHA.109.192521

56. Baldi JC, Wilson GA, Wilson LC, Wilkins GT, Lamberts RR. The type 2 diabetic heart: its role in exercise intolerance and the challenge to find effective exercise interventions. Sports Med (2016) 46(11):1–13. doi:10.1007/s40279-016-0542-9

57. Garber CE, Blissmer B, Deschenes MR, Franklin BA, Lamonte MJ, Lee I-M, et al. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise. Med Sci Sports Exerc (2011) 43(7):1334–59. doi:10.1249/MSS.0b013e318213fefb

58. Gibala MJ, Little JP, MacDonald MJ, Hawley JA. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol (2012) 590(5):1077–84. doi:10.1113/jphysiol.2011.224725

59. Weston KS, Wisloff U, Coombes JS. High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med (2014) 48(16):1227–34. doi:10.1136/ bjsports-2013-092576

60. Jelleyman C, Yates T, O’Donovan G, Gray L, King JA, Khunti K, et al. The effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis. Obes Rev (2015) 16(11):942–61. doi:10.1111/obr.12317

61. Ramos JS, Dalleck LC, Tjonna AE, Beetham KS, Coombes JS. The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis. Sports Med (2015) 45(5):679–92. doi:10.1007/s40279-015-0321-z

62. Tjonna AE, Lee SJ, Rognmo O, Stolen TO, Bye A, Haram PM, et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome. Circulation (2008) 118(4):346–54. doi:10.1161/ CIRCULATIONAHA.108.772822

63. Hollekim-Strand SM, Bjorgaas MR, Albrektsen G, Tjonna AE, Wisloff U, Ingul CB. High-intensity interval exercise effectively improves cardiac function in patients with type 2 diabetes mellitus and diastolic dysfunction. J Am Coll Cardiol (2014) 64(16):1758. doi:10.1016/j.jacc.2014.07.971

64. Stoa EM, Meling S, Nyhus L-K, Stromstad G, Mangerud KM, Helgerud J, et al. High-intensity aerobic interval training improves aerobic fitness and HbA1c among persons diagnosed with type 2 diabetes. Eur J Appl Physiol (2017) 117(3):455–67. doi:10.1007/s00421-017-3540-1

65. Karstoft K, Winding K, Knudsen SH, Nielsen JS, Thomsen C, Pedersen BK, et al. The effects of free-living interval-walking training on glycemic control, body composition, and physical fitness in type 2 diabetic patients a randomized, controlled trial. Diabetes Care (2013) 36(2):228–36. doi:10.2337/ dc12-0658

66. Apostolopoulou M, Röhling M, Gancheva S, Jelenik T, Kaul K, Bierwagen A, et al. High-intensity interval training improves peripheral insulin sensitivity and mitochondrial respiration in patients with type 2 diabetes. Diabetol Stoffwechsel (2016) 11(S 01):FV8. doi:10.1055/s-0036-1580755

67. Karstoft K, Winding K, Knudsen SH, James NG, Scheel MM, Olesen J, et al. Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomized controlled trial. Diabetologia (2014) 57(10):2081–93. doi:10.1007/s00125-014-3334-5

68. Garber AJ, Duncan TG, Goodman AM, Mills DJ, Rohlf JL. Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial. Am J Med (1997) 103(6):491–7. doi:10.1016/S0002-9343(97)00254-4