Evaluación y tratamiento de la lumbalgia

1. Murray CJ, Atkinson C, Bhalla K, et al; US Burden of Disease Collaborators. The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA. 2013; 310(6):591-608.
2. Henschke N, Kamper SJ, Maher CG. The epidemiology and economic consequences of pain. Mayo Clin Proc. 2015; 90(1): 139-147.
3. Fillingim RB, Bruehl S, Dworkin RH, et al. The ACTTIONAmerican Pain Society Pain Taxonomy (AAPT): an evidence-based and multidimensional approach to classifying chronic pain conditions. J Pain. 2014; 15(3):241-249.
4. Geurts JW. Classification and management of low back pain: Is this the right direction? Eur J Pain. 2015; 19(3):293-294.
5. Henriques AA, Dussán-Sarria JA, Botelho LM, Caumo W. Multidimensional approach to classifying chronic pain conditions –less is more. J Pain. 2014; 15(11):1199-1200.
6. DePalma MJ, Ketchum JM, Saullo T. What is the source of chronic low back pain and does age play a role? Pain Med. 2011; 12(2):224-233.
7. DePalma MJ, Ketchum JM, Saullo TR. Multivariable analyses of the relationships between age, gender, and body mass index and the source of chronic low back pain. Pain Med. 2012; 13(4): 498-506.
8. Cohen SP. Epidemiology, diagnosis, and treatment of neck pain. Mayo Clin Proc. 2015; 90(2):284-299.
9. Hoy D, Brooks P, Blyth F, Buchbinder R. The epidemiology of low back pain. Best Pract Res Clin Rheumatol. 2010; 24(6): 769-781.
10. Hoy D, Bain C, Williams G, et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012; 64(6):2028-2037.
11. Taylor JB, Goode AP, George SZ, Cook CE. Incidence and risk factors for first-time incident low back pain: a systematic review and meta-analysis. Spine J. 2014; 14(10):2299-2319.
12. Freynhagen R, Baron R, Gockel U, Tölle TR. painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin. 2006; 22(10):1911-1920.
13. El Sissi W, Arnaout A, Chaarani MW, et al. Prevalence of neuropathic pain among patients with chronic low-back pain in the Arabian Gulf Region assessed using the leeds assessment of neuropathic symptoms and signs pain scale. J Int Med Res. 2010; 38(6):2135-2145.
14. Beith ID, Kemp A, Kenyon J, Prout M, Chestnut TJ. Identifying neuropathic back and leg pain: a cross-sectional study. Pain. 2011; 152(7):1511-1516.
15. Kaki AM, El-Yaski AZ, Youseif E. Identifying neuropathic pain among patients with chronic low-back pain: use of the Leeds Assessment of Neuropathic Symptoms and Signs pain scale. Reg Anesth Pain Med. 2005; 30(5):422-428.
16. Hassan AE, Saleh HA, Baroudy YM, et al. Prevalence of neuropathic pain among patients suffering from chronic low back pain in Saudi Arabia. Saudi Med J. 2004; 25(12):1986-1990.
17. Cohen SP, Bicket MC, Jamison D, Wilkinson I, Rathmell JP. Epidural steroids: a comprehensive, evidence-based review. Reg Anesth Pain Med. 2013; 38(3):175-200.
18. Smith BH, Torrance N, Bennett MI, Lee AJ. Health and quality of life associated with chronic pain of predominantly neuropathic origin in the community. Clin J Pain. 2007; 23(2): 143-149.
19. Younes M, Béjia I, Aguir Z, et al. Prevalence and risk factors of disk-related sciatica in an urban population in Tunisia. Joint Bone Spine. 2006; 73(5):538-542.
20. Matsudaira K, Kawaguchi M, Isomura T, et al. Identification of risk factors for new-onset sciatica in Japanese workers: findings from the Japan epidemiological research of Occupation related Back pain study. Spine (Phila Pa 1976). 2013; 38(26):E1691-E1700.
21. Melancia JL, Francisco AF, Antunes JL. Spinal stenosis. Handb Clin Neurol. 2014; 119:541-549.
22. Henschke N, Maher CG, Refshauge KM, et al. Prognosis in patients with recent onset low back pain in Australian primary care: inception cohort study. BMJ. 2008; 337:a171.
23. Itz CJ, Geurts JW, van Kleef M, Nelemans P. Clinical course of non-specific low back pain: a systematic review of prospective cohort studies set in primary care. Eur J Pain. 2013; 17(1):5-15.
24. Hakelius A. Prognosis in sciatica: a clinical follow-up of surgical and non-surgical treatment. Acta Orthop Scand Suppl. 1970; 129:1-76.
25. Saal JA, Saal JS. Nonoperative treatment of herniated lumbar intervertebral disc with radiculopathy: an outcome study. Spine (Phila Pa 1976). 1989; 14(4):431-437.
26. Weber H, Holme I, Amlie E. The natural course of acute sciatica with nerve root symptoms in a double-blind placebo-controlled trial evaluating the effect of piroxicam. Spine (Phila Pa 1976). 1993; 18(11):1433-1438.
27. Fraser RD. Chymopapain for the treatment of intervertebral disc herniation: the final report of a double-blind study. Spine (Phila Pa 1976). 1984; 9(8):815-818.
28. Suri P, Rainville J, Hunter DJ, Li L, Katz JN. Recurrence of radicular pain or back pain after nonsurgical treatment of symptomatic lumbar disk herniation. Arch Phys Med Rehabil. 2012; 93(4):690-695.
29. Casey E. Natural history of radiculopathy. Phys Med Rehabil Clin N Am. 2011; 22(1):1-5.
30. Saal JA. Natural history and nonoperative treatment of lumbar disc herniation. Spine (Phila Pa 1976). 1996; 21(24 suppl):2S-9S.
31. Benoist M. The natural history of lumbar disc herniation and radiculopathy. Joint Bone Spine. 2002; 69(2):155-160.
32. Linton SJ, Boersma K. Early identification of patients at risk of developing a persistent back problem: the predictive validity of the Orebro Musculoskeletal Pain Questionnaire. Clin J Pain. 2003;19(2):80-86.
33. Sattelmayer M, Lorenz T, Röder C, Hilfiker R. Predictive value of the Acute Low Back Pain Screening Questionnaire and the Örebro Musculoskeletal Pain Screening Questionnaire for persisting problems. Eur Spine J. 2012; 21(suppl 6):S773-S784.
34. Minamide A, Yoshida M, Maio K. The natural clinical course of lumbar spinal stenosis: a longitudinal cohort study over a minimum of 10 years. J Orthop Sci. 2013; 18(5):693-698.
35. Micankova Adamova B, Vohanka S, Dusek L, Jarkovsky J, Bednarik J. Prediction of long-term clinical outcome in patients with lumbar spinal stenosis. Eur Spine J. 2012; 21(12):2611-2619.
36. Johnsson KE, Udén A, Rosén I. The effect of decompression on the natural course of spinal stenosis: a comparison of surgically treated and untreated patients. Spine (Phila Pa 1976). 1991; 16(6):615-619.
37. Johnsson KE, Rosén I, Udén A. The natural course of lumbar spinal stenosis. Clin Orthop Relat Res. 1992; 279:82-86.
38. Amundsen T, Weber H, Nordal HJ, Magnaes B, Abdelnoor M, Lilleâs F. Lumbar spinal stenosis: conservative or surgical management? A prospective 10-year study. Spine (Phila Pa 1976). 2000;25(11):1424-1435; discussion 1435-1426.
39. Konin GP, Walz DM. Lumbosacral transitional vertebrae: classification, imaging findings, and clinical relevance. AJNR Am J Neuroradiol. 2010; 31(10):1778-1786.
40. Taskaynatan MA, Izci Y, Ozgul A, Hazneci B, Dursun H, Kalyon TA. Clinical significance of congenital lumbosacral malformations in young male population with prolonged low back pain. Spine (Phila Pa 1976). 2005; 30(8):E210-E213.
41. Otani K, Konno S, Kikuchi S. Lumbosacral transitional vertebrae and nerve-root symptoms. J Bone Joint Surg Br. 2001; 83(8):1137-1140.
42. Tang M, Yang XF, Yang SW, et al. Lumbosacral transitional vertebra in a population-based study of 5860 individuals: prevalence and relationship to low back pain. Eur J Radiol. 2014; 83(9):1679-1682.
43. Nardo L, Alizai H, Virayavanich W, et al. Lumbosacral transitional vertebrae: association with low back pain. Radiology. 2012;265(2):497-503.
44. Roberts S, Menage J, Urban JP. Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc. Spine (Phila Pa 1976). 1989; 14(2):166-174.
45. Simon J, McAuliffe M, Shamim F, Vuong N, Tahaei A. Discogenic low back pain. Phys Med Rehabil Clin N Am. 2014; 25(2): 305-317.
46. Kallewaard JW, Terheggen MA, Groen GJ, et al. 15. Discogenic low back pain. Pain Pract. 2010; 10(6):560-579.
47. Cohen SP, Raja SN. Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain. Anesthesiology. 2007; 106(3):591-614.
48. Yang KH, King AI. Mechanism of facet load transmission as a hypothesis for low-back pain. Spine (Phila Pa 1976). 1984; 9(6):557-565.
49. Adams MA, Hutton WC. The mechanical function of the lumbar apophyseal joints. Spine (Phila Pa 1976). 1983; 8(3):327-330.
50. Izzo R, Guarnieri G, Guglielmi G, Muto M. Biomechanics of the spine. Part I: spinal stability. Eur J Radiol. 2013; 82(1): 118-126.
51. Gellhorn AC, Katz JN, Suri P. Osteoarthritis of the spine: the facet joints. Nat Rev Rheumatol. 2013; 9(4):216-224.
52. Kosaka H, Sairyo K, Biyani A, et al. Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis. Spine (Phila Pa 1976). 2007; 32(25):2805-2811.
53. Sairyo K, Biyani A, Goel V, et al. Pathomechanism of ligamentum flavum hypertrophy: a multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments. Spine (Phila Pa 1976). 2005; 30(23): 2649-2656.
54. Szpalski M, Gunzburg R. Lumbar spinal stenosis in the elderly: an overview. Eur Spine J. 2003; 12(suppl 2):S170-S175.
55. Bartleson J, Deen GH. Spine Disorders: Medical and Surgical Management. Cambridge: Cambridge University Press; 2009.
56. Leinonen V, Kankaanpää M, Luukkonen M, et al. Lumbar paraspinal muscle function, perception of lumbar position, and postural control in disc herniation-related back pain. Spine (Phila Pa 1976). 2003; 28(8):842-848.
57. Chan ST, Fung PK, Ng NY, et al. Dynamic changes of elasticity, cross-sectional area, and fat infiltration of multifidus at different postures in men with chronic low back pain. Spine J. 2012; 12(5):381-388.
58. Kalichman L, Hodges P, Li L, Guermazi A, Hunter DJ. Changes in paraspinal muscles and their association with low back pain and spinal degeneration: CT study. Eur Spine J. 2010; 19(7): 1136-1144.
59. Silfies SP, Squillante D, Maurer P,Westcott S, Karduna AR. Trunk muscle recruitment patterns in specific chronic low back pain populations. Clin Biomech (Bristol, Avon). 2005; 20(5):465-473.
60. Teichtahl AJ, Urquhart DM, Wang Y, et al. Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability.
Arthritis Res Ther. 2015; 17:114.
61. Deyo RA, Weinstein JN. Low back pain. N Engl J Med. 2001; 344(5):363-370.
62. Chou R, Qaseem A, Snow V, et al; Clinical Efficacy Assessment Subcommittee of the American College of Physicians; American College of Physicians; American Pain Society Low Back Pain Guidelines Panel. Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society [published correction appears in Ann Intern Med. 2008 (Correction: Diagnosis and treatment of low back pain.)]. Ann Intern Med. 2007; 147(7):478-491
63. Underwood M, Buchbinder R. Red flags for back pain. BMJ. 2013;347:f7432.
64. Henschke N, Maher CG, Refshauge KM, et al. Prevalence of and screening for serious spinal pathology in patients presenting to primary care settings with acute low back pain. Arthritis Rheum. 2009; 60(10):3072-3080.
65. Downie A, Williams CM, Henschke N, et al. Red flags to screen for malignancy and fracture in patients with low back pain: systematic review [published correction appears in BMJ. 2014;348:g7]. BMJ. 2013; 347:f7095.
66. Williams CM, Henschke N, Maher CG, et al. Red flags to screen for vertebral fracture in patients presenting with lowback pain. Cochrane Database Syst Rev. 2013;(1):CD008643.
67. Malik KM, Cohen SP, Walega DR, Benzon HT. Diagnostic criteria and treatment of discogenic pain: a systematic review of recent clinical literature. Spine J. 2013; 13(11):1675-1689.
68. Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. The prevalence and clinical features of internal disc disruption in patients with chronic low back pain. Spine (Phila Pa 1976). 1995; 20(17):1878-1883.
69. Depalma MJ, Ketchum JM, Trussell BS, Saullo TR,Slipman CW. Does the location of low back pain predict its source? PM R. 2011; 3(1):33-39.
70. Ohnmeiss DD, Vanharanta H, Ekholm J. Relation between pain location and disc pathology: a study of pain drawings and CT/discography. Clin J Pain. 1999; 15(3):210-217.
71. Schwarzer AC, Wang SC, Bogduk N, McNaught PJ, Laurent R. Prevalence and clinical features of lumbar zygapophysial joint pain: a study in an Australian population with chronic low back pain. Ann Rheum Dis. 1995; 54(2):100-106.
72. Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. Clinical features of patients with pain stemming from the lumbar zygapophysial joints: is the lumbar facet syndrome a clinical entity? Spine (Phila Pa 1976). 1994; 19(10): 1132-1137.
73. Laslett M, McDonald B, Aprill CN, Tropp H, Oberg B. Clinical predictors of screening lumbar zygapophyseal joint blocks: development of clinical prediction rules. Spine J. 2006;6(4): 370-379.
74. Ianuzzi A, Little JS, Chiu JB, Baitner A, Kawchuk G, Khalsa PS. Human lumbar facet joint capsule strains: I. During physiological motions. Spine J. 2004; 4(2):141-152.
75. Revel M, Poiraudeau S, Auleley GR, et al. Capacity of the clinical picture to characterize low back pain relieved by facet joint anesthesia: proposed criteria to identify patients with painful facet joints. Spine (Phila Pa 1976). 1998; 23(18):1972-1976; discussion 1977.
76. Cohen SP, Hurley RW, Christo PJ, Winkley J, Mohiuddin MM, Stojanovic MP. Clinical predictors of success and failure for lumbar facet radiofrequency denervation. Clin J Pain. 2007; 23(1):45-52.
77. Maigne JY, Aivaliklis A, Pfefer F. Results of sacroiliac joint double block and value of sacroiliac pain provocation tests in 54 patients with low back pain. Spine (Phila Pa 1976). 1996; 21(16):1889-1892.
78. Cohen SP, Chen Y, Neufeld NJ. Sacroiliac joint pain: a comprehensive review of epidemiology, diagnosis and treatment. Expert Rev Neurother. 2013; 13(1):99-116.
79. Slipman CW, Jackson HB, Lipetz JS, Chan KT, Lenrow D, Vresilovic EJ. Sacroiliac joint pain referral zones. Arch Phys Med Rehabil. 2000; 81(3):334-338.
80. Young S, Aprill C, Laslett M. Correlation of clinical examination characteristics with three sources of chronic low back pain. Spine J. 2003; 3(6):460-465.
81. Laslett M, Aprill CN, McDonald B, Young SB. Diagnosis of sacroiliac joint pain: validity of individual provocation tests and composites of tests. Man Ther. 2005; 10(3):207-218.
82. van der Wurff P, Buijs EJ, Groen GJ. A multitest regimen of pain provocation tests as an aid to reduce unnecessary minimally invasive sacroiliac joint procedures. Arch Phys Med Rehabil. 2006;87(1):10-14.
83. Szadek KM, van der Wurff P, van Tulder MW, Zuurmond WW, Perez RS. Diagnostic validity of criteria for sacroiliac joint pain: a systematic review. J Pain. 2009; 10(4): 354-368.
84. Michel F, Decavel P, Toussirot E, et al. Piriformis muscle syndrome: diagnostic criteria and treatment of a monocentric series of 250 patients. Ann Phys Rehabil Med. 2013; 56(5): 371-383.
85. Vora AJ, Doerr KD, Wolfer LR. Functional anatomy and pathophysiology of axial low back pain: disc, posterior elements, sacroiliac joint, and associated pain generators. Phys Med Rehabil Clin N Am. 2010; 21(4):679-709.
86. Malanga GA, Cruz Colon EJ. Myofascial low back pain: a review. Phys Med Rehabil Clin N Am. 2010; 21(4):711-724.
87. Leone A, Cianfoni A, Cerase A, Magarelli N, Bonomo L. Lumbar spondylolysis: a review. Skeletal Radiol. 2011; 40(6): 683-700.
88. Koes BW, van Tulder MW, Peul WC. Diagnosis and treatment of sciatica. BMJ. 2007; 334(7607):1313-1317.
89. Czyrny JJ, Lawrence J. The importance of paraspinal muscle EMG in cervical and lumbosacral radiculopathy: review of 100 cases. Electromyogr Clin Neurophysiol. 1996;36(8): 503-508.
90. Vroomen PC, de Krom MC, Knottnerus JA. Diagnostic value of history and physical examination in patients suspected of sciatica due to disc herniation: a systematic review. J Neurol. 1999; 246(10):899-906.
91. van der Windt DA, Simons E, Riphagen II, et al. Physical examination for lumbar radiculopathy due to disc herniation in patients with low-back pain. Cochrane Database Syst Rev. 2010; (2):CD007431.
92. Gardner A, Gardner E, Morley T. Cauda equina syndrome: a review of the current clinical and medico-legal position. Eur Spine J. 2011; 20(5):690-697.
93. Katz JN, Dalgas M, Stucki G, et al. Degenerative lumbar spinal stenosis. Diagnostic value of the history and physical examination. Arthritis Rheum. 1995; 38(9):1236-1241.
94. Suri P, Rainville J, Kalichman L, Katz JN. Does this older adult with lower extremity pain have the clinical syndrome of lumbar spinal stenosis? JAMA. 2010; 304(23):2628-2636.
95. Kobayashi S. Pathophysiology, diagnosis and treatment of intermittent claudication in patients with lumbar canal stenosis. World J Orthop. 2014; 5(2):134-145.
96. Katz JN, Harris MB. Clinical practice: lumbar spinal stenosis. N Engl J Med. 2008; 358(8):818-825.
97. Nadeau M, Rosas-Arellano MP, Gurr KR, et al. The reliability of differentiating neurogenic claudication from vascular claudication based on symptomatic presentation. Can J Surg. 2013; 56(6):372-377.
98. Bigos S, Bowyer O, Braen G, et al. Acute Low Back Problems in Adults. Rockville, MD: Agency for Health Care Policy and Research, Public Health Service, US Dept of Health and Human Services; December 1994. Clinical Practie Guidline No. 14. AHCPR Publication No. 95-0642.
99. Deyo RA. Cascade effects of medical technology. Annu Rev Public Health. 2002; 23:23-44.
100. Chou R, Fu R, Carrino JA, Deyo RA. Imaging strategies for low-back pain: systematic review and meta-analysis. Lancet. 2009; 373(9662):463-472.
101. Jarvik JG, Gold LS, Comstock BA, et al. Association of early imaging for back pain with clinical outcomes in older adults [published corrections appear in JAMA. 2015 (Incorrect alignment and omitted data in tables)]. JAMA. 2015; 313(11): 1143-1153.
102. Cohen SP, Gupta A, Strassels SA, et al. Effect of MRI on treatment results or decision making in patients with lumbosacral radiculopathy referred for epidural steroid injections: a multicenter, randomized controlled trial [published correction appears in Arch Intern Med. 2012;172(8):673].  Arch Intern Med. 2012; 172(2):134-142.
103. Graves JM, Fulton-Kehoe D, Jarvik JG, Franklin GM. Health care utilization and costs associated with adherence to clinical practice guidelines for early magnetic resonance imaging among workers with acute occupational low back pain. Health
Serv Res. 2014; 49(2):645-665.
104. Ash LM, Modic MT, Obuchowski NA, Ross JS, Brant- Zawadzki MN, Grooff PN. Effects of diagnostic information, per se, on patient outcomes in acute radiculopathy and low back pain. AJNR Am J Neuroradiol. 2008; 29(6):1098-1103.
105. Chou R, Qaseem A, Owens DK, Shekelle P; Clinical Guidelines Committee of the American College of Physicians. Diagnostic imaging for low back pain: advice for high-value health care from the American College of Physicians [published correction appears in Ann Intern Med. 2012; 156(1, pt 1):71]. Ann Intern Med. 2011; 154(3):181-189.
106. Sandoval AE. Electrodiagnostics for low back pain. Phys Med Rehabil Clin N Am. 2010; 21(4):767-776.
107. Haig AJ, Geisser ME, Tong HC, et al. Electromyographic and magnetic resonance imaging to predict lumbar stenosis, low back pain, and no back symptoms. J Bone Joint Surg Am. 2007;89(2):358-366.
108. Reza Soltani Z, Sajadi S, Tavana B. A comparison of magnetic resonance imaging with electrodiagnostic findings in the evaluation of clinical radiculopathy: a cross-sectional study. Eur Spine J. 2014; 23(4):916-921.
109. Plastaras CT, Joshi AB. The electrodiagnostic evaluation of radiculopathy. Phys Med Rehabil Clin N Am. 2011; 22(1):59-74.
110. Mondelli M, Aretini A, Arrigucci U, Ginanneschi F, Greco G, Sicurelli F. Clinical findings and electrodiagnostic testing in 108 consecutive cases of lumbosacral radiculopathy due to herniated disc. Neurophysiol Clin. 2013; 43(4): 205-215.
111. Plastaras CT. Electrodiagnostic challenges in the evaluation of lumbar spinal stenosis. Phys Med Rehabil Clin N Am. 2003; 14(1):57-69.
112. Cohen SP, Hurley RW, Buckenmaier CC III, Kurihara C, Morlando B, Dragovich A. Randomized placebo-controlled study evaluating lateral branch radiofrequency denervation for sacroiliac joint pain. Anesthesiology. 2008; 109(2):279-288.
113. Cohen SP, Williams KA, Kurihara C, et al. Multicenter, randomized, comparative cost-effectiveness study comparing 0, 1, and 2 diagnostic medial branch (facet joint nerve) block treatment paradigms before lumbar facet radiofrequency denervation. Anesthesiology. 2010; 113(2):395-405.
114. Provenzano DA. Diagnostic discography: what is the clinical utility? Curr Pain Headache Rep. 2012; 16(1):26-34.
115. Margetic P, Pavic R, Stancic MF. Provocative discography screening improves surgical outcome. Wien Klin Wochenschr. 2013; 125(19-20):600-610.
116. Yeom JS, Lee JW, Park KW, et al. Value of diagnostic lumbar selective nerve root block: a prospective controlled study. AJNR Am J Neuroradiol. 2008; 29(5):1017-1023.
117. Kuijpers T, van Middelkoop M, Rubinstein SM, et al. A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain. Eur Spine J. 2011; 20(1):40-50.
118. van Tulder MW, Touray T, Furlan AD, Solway S, Bouter LM; Cochrane Back Review Group. Muscle relaxants for nonspecific low back pain: a systematic review within the framework of the Cochrane collaboration. Spine (Phila Pa 1976). 2003; 28(17):1978-1992.
119. Williamson OD, Sagman D, Bruins RH, Boulay LJ, Schacht A. Antidepressants in the treatment for chronic low back pain: questioning the validity of meta-analyses. Pain Pract. 2014; 14(2):E33-E41.
120. Finnerup NB, Sindrup SH, Jensen TS. The evidence for pharmacological treatment of neuropathic pain. Pain. 2010;150(3): 573-581.
121. Lasko B, Levitt RJ, Rainsford KD, Bouchard S, Rozova A, Robertson S. Extended-release tramadol/paracetamol in moderate-to-severe pain: a randomized, placebo-controlled study in patients with acute low back pain. Curr Med Res Opin. 2012; 28(5):847-857.
122. Biondi D, Xiang J, Benson C, Etropolski M, Moskovitz B, Rauschkolb C. Tapentadol immediate release versus oxycodone immediate release for treatment of acute low back pain. Pain Physician. 2013; 16(3):E237-E246.
123. Chaparro LE, Furlan AD, Deshpande A, Mailis-Gagnon A, Atlas S, Turk DC. Opioids compared to placebo or other treatments for chronic low-back pain. Cochrane Database Syst Rev. 2013; (8):CD004959.
124. Baron R, Freynhagen R, Tölle TR, et al; A0081007 Investigators. The efficacy and safety of pregabalin in the treatment of neuropathic pain associated with chronic lumbosacral radiculopathy. Pain. 2010; 150(3):420-427.
125. Zhou M, Chen N, He L, Yang M, Zhu C, Wu F. Oxcarbazepine for neuropathic pain. Cochrane Database Syst Rev. 2013; (3):CD007963.
126. Khoromi S, Patsalides A, Parada S, Salehi V, Meegan JM, Max MB. Topiramate in chronic lumbar radicular pain. J Pain. 2005;6(12): 829-836.
127. O’Connor AB, Dworkin RH. Treatment of neuropathic pain: an overview of recent guidelines. Am J Med. 2009; 122 (10 suppl): S22-S32.
128. Khoromi S, Cui L, Nackers L, Max MB. Morphine, nortriptyline and their combination vs. placebo in patients with chronic lumbar root pain. Pain. 2007; 130(1-2):66-75.
129. Cawston H, Davie A, Paget MA, Skljarevski V, Happich M. Efficacy of duloxetine versus alternative oral therapies: an indirect comparison of randomised clinical trials in chronic low back pain. Eur Spine J. 2013; 22(9):1996-2009.
130. Urquhart DM, Zheng Y, Cheng AC, et al. Could low grade bacterial infection contribute to low back pain? A systematic review. BMC Med. 2015; 13:13.
131. Albert HB, Sorensen JS, Christensen BS, Manniche C. Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a doubleblind randomized clinical controlled trial of efficacy. Eur Spine J. 2013; 22(4):697-707.
132. Albert HB, Kjaer P, Jensen TS, Sorensen JS, Bendix T, Manniche C. Modic changes, possible causes and relation to low back pain. Med Hypotheses. 2008; 70(2):361-368.
133. Manchikanti L, Falco FJ, Singh V, et al. Utilization of interventional techniques in managing chronic pain in the Medicare population: analysis of growth patterns from 2000 to 2011. Pain Physician. 2012; 15(6):E969-E982.
134. Deyo RA, Mirza SK, Turner JA, Martin BI. Overtreating chronic back pain: time to back off? J Am Board Fam Med. 2009; 22(1): 62-68.
135. Hansen H, Manchikanti L, Simopoulos TT, et al. A systematic evaluation of the therapeutic effectiveness of sacroiliac joint interventions. Pain Physician. 2012; 15(3):E247-E278.
136. Khot A, Bowditch M, Powell J, Sharp D. The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial. Spine (Phila Pa 1976). 2004; 29(8):833-836; discussion 837.
137. Simmons JW, McMillin JN, Emery SF, Kimmich SJ. Intradiscal steroids: a prospective double-blind clinical trial. Spine (Phila Pa 1976). 1992; 17(6 suppl):S172-S175.
138. Cohen SP, Wenzell D, Hurley RW, et al. A double-blind, placebo-controlled, dose-response pilot study evaluating intradiscal etanercept in patients with chronic discogenic low back pain or lumbosacral radiculopathy. Anesthesiology. 2007; 107(1): 99-105.
139. Peng B, Pang X, Wu Y, Zhao C, Song X. A randomized placebo-controlled trial of intradiscal methylene blue injection for the treatment of chronic discogenic low back pain. Pain. 2010;149 (1):124-129.
140. Gupta G, Radhakrishna M, Chankowsky J, Asenjo JF. Methylene blue in the treatment of discogenic low back pain. Pain Physician. 2012; 15(4):333-338.
141. Kim SH, Ahn SH, Cho YW, Lee DG. Effect of intradiscal methylene blue injection for the chronic discogenic low back pain: one year prospective follow-up study. Ann Rehabil Med. 2012; 36(5):657-664.
142. Pauza KJ, Howell S, Dreyfuss P, Peloza JH, Dawson K, Bogduk N. A randomized, placebo-controlled trial of intradiscal electrothermal therapy for the treatment of discogenic low back pain. Spine J. 2004; 4(1):27-35.
143. Freeman BJ, Fraser RD, Cain CM, Hall DJ, Chapple DC. A randomized, double-blind, controlled trial: intradiscal electrothermal therapy versus placebo for the treatment of chronic discogenic low back pain. Spine (Phila Pa 1976).
2005; 30(21):2369-2377; discussion 2378.
144. Kvarstein G, Måwe L, Indahl A, et al. A randomized double-blind controlled trial of intra-annular radiofrequency thermal disc therapyda 12-month follow-up. Pain. 2009; 145(3):279-286.
145. Freedman BA, Cohen SP, Kuklo TR, Lehman RA, Larkin P, Giuliani JR. Intradiscal electrothermal therapy (IDET) for chronic low back pain in active-duty soldiers: 2-year followup. Spine J. 2003; 3(6):502-509.
146. Kapural L, Vrooman B, Sarwar S, et al. Radiofrequency intradiscal biacuplasty for treatment of discogenic lower back pain: a 12-month follow-up. Pain Med. 2015; 16(3):425-431.
147. Waseem Z, Boulias C, Gordon A, Ismail F, Sheean G, Furlan AD. Botulinum toxin injections for low-back pain and sciatica. Cochrane Database Syst Rev. 2011 ;(1):CD008257.
148. Staal JB, de Bie RA, de Vet HC, Hildebrandt J, Nelemans P. Injection therapy for subacute and chronic low back pain: an updated Cochrane review. Spine (Phila Pa 1976). 2009; 34(1):49-59.
149. Jamison RN, VadeBoncouer T, Ferrante FM. Low back pain patients unresponsive to an epidural steroid injection: identifying predictive factors. Clin J Pain. 1991;7(4):311-317. 
150. Hopwood MB, Abram SE. Factors associated with failure of lumbar epidural steroids. Reg Anesth. 1993; 18(4):238-243.
151. Kirpalani D, Mitra R. Is chronic opioid use a negative predictive factor for response to cervical epidural steroid injections? J Back Musculoskelet Rehabil. 2011; 24(3):123-127.
152. Bicket MC, Horowitz JM, Benzon HT, Cohen SP. Epidural injections in prevention of surgery for spinal pain: systematic review and meta-analysis of randomized controlled trials. Spine J. 2015; 15(2):348-362.
153. Riew KD, Park JB, Cho YS, et al. Nerve root blocks in the treatment of lumbar radicular pain: a minimum five-year follow-up. J Bone Joint Surg Am. 2006; 88(8):1722-1725.
154. Atluri S, Glaser SE, Shah RV, Sudarshan G. Needle position analysis in cases of paralysis from transforaminal epidurals: consider alternative approaches to traditional technique. Pain Physician. 2013; 16(4):321-334.
155. Cohen SP, White RL, Kurihara C, et al. Epidural steroids, etanercept, or saline in subacute sciatica: a multicenter, randomized trial. Ann Intern Med. 2012; 156(8):551-559.
156. Ohtori S, Miyagi M, Eguchi Y, et al. Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: a prospective randomized study. Spine (Phila Pa 1976). 2012;37(6): 439-444.
157. Freeman BJ, LudbrookGL,Hall S, et al. Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation. Spine (Phila Pa 1976). 2013; 38(23):1986-1994.
158. Searle A, Spink M, Ho A, Chuter V. Exercise interventions for the treatment of chronic low back pain: a systematic review and meta-analysis of randomised controlled trials [published online ahead of print February 13, 2015]. Clin Rehabil. doi: 10.1177/0269215515570379.
159. Lawford BJ, Walters J, Ferrar K. Does walking improve disability status, function, or quality of life in adults with chronic low back pain? A systematic review [published online ahead of print June 18, 2015]. Clin Rehabil. doi:10.1177/0269215515590487.
160. Cramer H, Lauche R, Haller H, Dobos G. A systematic review and meta-analysis of yoga for low back pain. Clin J Pain. 2013; 29(5):450-460.
161. Wells C, Kolt GS, Marshall P, Hill B, Bialocerkowski A. The effectiveness of Pilates exercise in people with chronic low back pain: a systematic review. PLoS One. 2014;9(7): e100402.
162. Slade SC, Patel S, Underwood M, Keating JL. What are patient beliefs and perceptions about exercise for nonspecific chronic low back pain? A systematic review of qualitative studies. Clin J Pain. 2014; 30(11):995-1005.
163. Furlan AD, Imamura M, Dryden T, Irvin E. Massage for low back pain: an updated systematic review within the framework of the Cochrane Back Review Group. Spine (Phila Pa 1976). 2009; 34(16):1669-1684.
164. Lam M, Galvin R, Curry P. Effectiveness of acupuncture for nonspecific chronic low back pain: a systematic review and meta-analysis. Spine (Phila Pa 1976). 2013; 38(24):2124-2138.
165. Ebadi S, Henschke N, Nakhostin Ansari N, Fallah E, van Tulder MW. Therapeutic ultrasound for chronic low-back pain. Cochrane Database Syst Rev. 2014; (3):CD009169.
166. Franke H, Franke JD, Fryer G. Osteopathic manipulative treatment for nonspecific low back pain: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2014; 15:286.
167. Franke H, Fryer G, Ostelo RW, Kamper SJ. Muscle energy technique for non-specific low-back pain. Cochrane Database Syst Rev. 2015; (2):CD009852.
168. Kizhakkeveettil A, Rose K, Kadar GE. Integrative therapies for low back pain that include complementary and alternative medicine care: a systematic review. Glob Adv Health Med. 2014; 3(5):49-64.
169. Rubinstein SM, van Middelkoop M, Kuijpers T, et al. A systematic review on the effectiveness of complementary and alternative medicine for chronic non-specific low-back pain. Eur Spine J. 2010; 19(8):1213-1228.
170. Khadilkar A, Odebiyi DO, Brosseau L, Wells GA. Transcutaneous electrical nerve stimulation (TENS) versus placebo for chronic low-back pain. Cochrane Database Syst Rev. 2008; (4): CD003008.
171. Dubinsky RM, Miyasaki J. Assessment: efficacy of transcutaneous electric nerve stimulation in the treatment of pain in neurologic disorders (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology. 2010; 74(2):173-176.
172. Snelgrove S, Liossi C. Living with chronic low back pain: a metasynthesis of qualitative research. Chronic Illn. 2013;9(4): 283-301.
173. Kamper SJ, Apeldoorn AT, Chiarotto A, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain. Cochrane Database Syst Rev. 2014; (9):CD000963.
174. Henschke N, Ostelo RW, van Tulder MW, et al. Behavioural treatment for chronic low-back pain. Cochrane Database Syst Rev. 2010; (7):CD002014.
175. Cramer H, Haller H, Lauche R, Dobos G. Mindfulness-based stress reduction for low back pain: a systematic review. BMC Complement Altern Med. 2012; 12:162.
176. Pannell WC, Savin DD, Scott TP, Wang JC, Daubs MD. Trends in the surgical treatment of lumbar spine disease in the United States. Spine J. 2015; 15(8):1719-1727.
177. Mroz TE, Lubelski D, Williams SK, et al. Differences in the surgical treatment of recurrent lumbar disc herniation among spine surgeons in the United States. Spine J. 2014; 14(10): 2334-2343.
178. Jacobs WC, van Tulder M, Arts M, et al. Surgery versus conservative management of sciatica due to a lumbar herniated disc: a systematic review. Eur Spine J. 2011; 20(4):513-522.
179. Kovacs FM, Urrútia G, Alarcón JD. Surgery versus conservative treatment for symptomatic lumbar spinal stenosis: a systematic review of randomized controlled trials. Spine (Phila Pa 1976). 2011; 36(20):E1335-E1351.
180. Chou R, Baisden J, Carragee EJ, Resnick DK, Shaffer WO, Loeser JD. Surgery for low back pain: a review of the evidence for an American Pain Society Clinical Practice Guideline. Spine (Phila Pa 1976). 2009; 34(10):1094-1109.
181. Machado GC, Ferreira PH, Harris IA, et al. Effectiveness of surgery for lumbar spinal stenosis: a systematic review and metaanalysis. PLoS One. 2015; 10(3):e0122800.
182. Ibrahim T, Tleyjeh IM, Gabbar O. Surgical versus nonsurgical treatment of chronic low back pain: a metaanalysis of randomised trials [published correction appears in Int Orthop. 2009; 33(2):589-590]. Int Orthop. 2008; 32(1): 107-113.
183. Mirza SK, Deyo RA. Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain. Spine (Phila Pa 1976). 2007; 32(7):816-823.
184. Wei J, Song Y, Sun L, Lv C. Comparison of artificial total disc replacement versus fusion for lumbar degenerative disc disease: a meta-analysis of randomized controlled trials. Int Orthop. 2013; 37(7):1315-1325.
185. Hellum C, Johnsen LG, Storheim K, et al. Surgery with disc prosthesis versus rehabilitation in patients with low back pain and degenerative disc: two year follow-up of randomized study. BMJ. 2011; 342:d2786.
186. Pope JE, Falowski S, Deer TR. Advanced waveforms and frequency with spinal cord stimulation: burst and highfrequency energy delivery. Expert Rev Med Devices. 2015; 12 (4):431-437.
187. Deer TR, Mekhail N, Provenzano D, et al; Neuromodulation Appropriateness Consensus Committee. The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee. Neuromodulation. 2014; 17(6):515-550; discussion 550.
188. Kapural L, Yu C, Doust MW, et al. Novel 10-kHz high frequency therapy (HF10 Therapy) Is Superior to traditional low-frequency spinal cord stimulation for the treatment of chronic back and leg pain: The SENZA-RCT randomized controlled trial. Anesthesiology. 2015; 123(4):851-860.
189. Prager J, Deer T, Levy R, et al. Best practices for intrathecal drug delivery for pain. Neuromodulation. 2014; 17(4):354-372; discussion 372.
190. Deer TR, Prager J, Levy R, et al. Polyanalgesic Consensus Conference 2012: recommendations for the management of pain by intrathecal (intraspinal) drug delivery: report of an interdisciplinary expert panel. Neuromodulation. 2012; 15(5):436-464;
discussion 464-466.