Ventajas y desventajas del uso | 23 NOV 15

Solución salina hipertónica nebulizada para bronquiolitis aguda

Evaluación de la eficacia y seguridad de la solución salina hipertónica nebulizada en la bronquiolitis aguda.
Autor/a: Zhang L1, Mendoza-Sassi RA2, Klassen TP3, Wainwright C4. Pediatrics. 2015 Oct;136(4):687-701
INDICE:  1.  | 2. 

1. Pelletier AJ, Mansbach JM, Camargo CA Jr. Direct medical costs of bronchiolitis hospitalizations in the United States. Pediatrics. 2006; 118(6):2418–2423
2. Shay DK, Holman RC, Newman RD, Liu LL, Stout JW, Anderson LJ. Bronchiolitis associated
hospitalizations among US children, 1980-1996. JAMA. 1999; 282(15):1440–1446
3. Mansbach JM, Emond JA, Camargo CA Jr. Bronchiolitis in US emergency departments 1992 to 2000: epidemiology and practice variation. Pediatr Emerg Care. 2005; 21(4):242–247
4. Everard ML, Hind D, Ugonna K, et al; SABRE Study Team. SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalized with acute bronchiolitis. Thorax. 2014; 69(12):1105–1112
5. Nair H, Nokes DJ, Gessner BD, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010; 375(9725):1545–1555
6. Wohl ME, Chernick V. Treatment of acute bronchiolitis. N Engl J Med. 2003; 349(1): 82–83
7. Wainwright C. Acute viral bronchiolitis in children—a very common condition with few therapeutic options. Paediatr Respir Rev. 2010; 11(1):39–45, quiz 45
8. Mandelberg A, Amirav I. Hypertonic saline or high volume normal saline for viral bronchiolitis: mechanisms and rationale. Pediatr Pulmonol. 2010; 45(1): 36–40
9. Sarrell EM, Tal G, Witzling M, et al. Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms. Chest. 2002; 122(6):2015–2020
10. Mandelberg A, Tal G, Witzling M, et al. Nebulized 3% hypertonic saline solution treatment in hospitalized infants with viral bronchiolitis. Chest. 2003; 123(2): 481–487
11. Tal G, Cesar K, Oron A, Houri S, Ballin A, Mandelberg A. Hypertonic saline/epinephrine treatment in hospitalized infants with viral bronchiolitis reduces hospitalization stay: 2 years experience. Isr Med Assoc J. 2006; 8(3): 169–173
12. Kuzik BA, Al-Qadhi SA, Kent S, et al. Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants. J Pediatr. 2007; 151(3):266–270, 270.e1
13. Grewal S, Ali S, McConnell DW, Vandermeer B, Klassen TP. A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department. Arch Pediatr Adolesc Med. 2009; 163(11):1007–1012
14. Al-Ansari K, Sakran M, Davidson BL, El Sayyed R, Mahjoub H, Ibrahim K. Nebulized 5% or 3% hypertonic or 0.9% saline for treating acute bronchiolitis in infants. J Pediatr. 2010; 157(4):630–634, 634.e1
15. Anil AB, Anil M, Saglam AB, Cetin N, Bal A, Aksu N. High volume normal saline alone is as effective as nebulized salbutamol normal saline, epinephrine-normal saline, and 3% saline in mild bronchiolitis. Pediatr Pulmonol. 2010; 45(1):41–47
16. Miraglia Del Giudice M, Saitta F, Leonardi S, et al. Effectiveness of nebulized hypertonic saline and epinephrine in hospitalized infants with bronchiolitis. Int J Immunopathol Pharmacol. 2012; 25(2):485–491
17. Ipek IO, Yalcin EU, Sezer RG, Bozaykut A. The efficacy of nebulized salbutamol, hypertonic saline and salbutamol/hypertonic saline combination in moderate bronchiolitis. Pulm Pharmacol
Ther. 2011; 24(6):633–637
18. Luo Z, Liu E, Luo J, et al. Nebulized hypertonic saline/salbutamol solution treatment in hospitalized children with mild to moderate bronchiolitis. Pediatr Int. 2010; 52(2):199–202
19. Luo Z, Fu Z, Liu E, et al. Nebulized hypertonic saline treatment in hospitalized children with moderate to severe viral bronchiolitis. Clin Microbiol Infect. 2011; 17(12):1829–1833
20. Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP. Nebulized hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database Syst Rev. 2008; (4):CD006458
21. Grewal S, Klassen TP. The tale of 2 trials: disentangling contradictory evidence on hypertonic saline for acute bronchiolitis. JAMA Pediatr. 2014; 168(7): 607–609
22. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009; 339:b2700
23. Sharma BS, Gupta MK, Rafik SP. Hypertonic (3%) saline vs 0.93% saline nebulization for acute viral bronchiolitis: a randomized controlled trial. Indian Pediatr. 2013; 50(8):743–747
24. Teunissen J, Hochs AH, Vaessen-Verberne A, et al. The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial. Eur Respir J. 2014; 44(4):913–921
25. NCT01488448 trial. Available at: https://clinicaltrials.gov/ct2/show/NCT01488448. Accessed January 5, 2015
26. Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol. 2014; 14:135
27. Tinsa F, Abdelkafi S, Bel Haj I, et al. A randomized, controlled trial of nebulized 5% hypertonic saline and mixed 5% hypertonic saline with epinephrine in bronchiolitis. Tunis Med. 2014; 92(11): 674–677
28. Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available at: www. cochrane-handbook.org. Accessed May 1, 2013
29. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003; 327(7414): 557–560
30. Wu S, Baker C, Lang ME, et al. Nebulized hypertonic saline for bronchiolitis: a randomized clinical trial. JAMA Pediatr. 2014; 168(7):657–663
31. Florin TA, Shaw KN, Kittick M, Yakscoe S, Zorc JJ. Nebulized hypertonic saline for bronchiolitis in the emergency department: a randomized clinical trial. JAMA Pediatr. 2014; 168(7): 664–670
32. Jacobs JD, Foster M, Wan J, Pershad J. 7% Hypertonic saline in acute bronchiolitis: a randomized controlled trial. Pediatrics. 2014; 133(1).
Available at: www.pediatrics.org/cgi/content/full/133/ 1/e8
33. Ojha AR, Mathema S, Sah S, Aryal UR. A comparative study on use of 3% saline versus 0.9% saline nebulization in children with bronchiolitis. J Nepal Health Res Counc. 2014; 12(26): 39–43
34. Pandit S, Dhawan N, Thakur D. Utility of hypertonic saline in the management of acute bronchiolitis in infants: a randomized controlled study. Int J Clin Pediatr. 2013; 2(1):24–29
35. Li G, Zhao J. Effectiveness of inhaled hypertonic saline in children with bronchiolitis [in Chinese]. Zhonghua Er Ke Za Zhi. 2014; 52(8):607–610
36. NCT01276821 trial. Available at: https://clinicaltrials.gov/ct2/show/NCT01276821. Accessed January 5, 2015
37. NCT01238848 trial. Available at: https://clinicaltrials.gov/ct2/show/NCT01238848. Accessed January 5, 2015
38. Lowell DI, Lister G, Von Koss H, McCarthy P. Wheezing in infants: the response toepinephrine. Pediatrics. 1987; 79(6): 939–945
39. Wang EE, Milner RA, Navas L, Maj H. Observer agreement for respiratory signs and oximetry in infants hospitalized with lower respiratory infections. Am Rev Respir Dis. 1992; 145(1):106–109
40. Amirav I, Newhouse MT. Aerosol therapy in infants and toddlers: past, present and future. Expert Rev Respir Med. 2008; 2(5):597–605
41. Hess D, Fisher D, Williams P, Pooler S, Kacmarek RM. Medication nebulizer performance. Effects of diluents volume, nebulizer flow, and nebulizer brand. Chest. 1996; 110(2): 498–505
42. Guyatt G, Oxman AD, Sultan S, et al. GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes. J Clin Epidemiol. 2013; 66(2): 151–157

 

Comentarios

Para ver los comentarios de sus colegas o para expresar su opinión debe ingresar con su cuenta de IntraMed.

AAIP RNBD
Términos y condiciones de uso | Política de privacidad | Todos los derechos reservados | Copyright 1997-2024