Fisiopatología y manejo médico | 11 ABR 23

Falla hepática aguda en niños

Revisión sobre los avances en el manejo médico de la falla hepática aguda promoviendo la conservación del hígado nativo
Autor/a: Akash Deep, Emma C Alexander, Yonca Bulut, Emer Fitzpatrick, Serge Grazioli, Nigel Heaton, Anil Dhawan  Lancet Child Adolesc Health 2022
INDICE:  1. Texto principal | 2. Texto principal
Texto principal

1 Squires RH Jr, Shneider BL, Bucuvalas J, et al. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr 2006; 148: 652–58.

2 Bhatt H, Rao GS. Management of acute liver failure: a pediatric perspective. Curr Pediatr Rep 2018; 6: 246–57.

3 Stravitz RT, Lee WM. Acute liver failure. Lancet 2019; 394: 869–81.

4 Kulkarni S, Perez C, Pichardo C, et al. Use of Pediatric Health Information System database to study the trends in the incidence, management, etiology, and outcomes due to pediatric acute liver failure in the United States from 2008 to 2013. Pediatr Transplant 2015; 19: 888–95.

5 Jain V, Dhawan A. Prognostic modeling in pediatric acute liver failure. Liver Transpl 2016; 22: 1418–30.

6 Miloh T, Barton A, Wheeler J, et al. Immunosuppression in pediatric liver transplant recipients: unique aspects. Liver Transpl 2017; 23: 244–56.

7 Albrecht J, Norenberg MD. Glutamine: a Trojan horse in ammonia neurotoxicity. Hepatology 2006; 44: 788–94.

8 Jayakumar AR, Rama Rao KV, Norenberg MD. Neuroinflammation in hepatic encephalopathy: mechanistic aspects. J Clin Exp Hepatol 2015; 5 (suppl 1): S21–28.

9 Bhatia V, Singh R, Acharya SK. Predictive value of arterial ammonia for complications and outcome in acute liver failure. Gut 2006; 55: 98–104.

10 Bernal W, Hall C, Karvellas CJ, Auzinger G, Sizer E, Wendon J. Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure. Hepatology 2007; 46: 1844–52.

11 Bernal W, Hyyrylainen A, Gera A, et al. Lessons from look-back in acute liver failure? A single centre experience of 3300 patients. J Hepatol 2013; 59: 74–80.

12 Crispe IN. The liver as a lymphoid organ. Annu Rev Immunol 2009; 27: 147–63.

13 Bilzer M, Roggel F, Gerbes AL. Role of Kupffer cells in host defense and liver disease. Liver Int 2006; 26: 1175–86.

14 Dong V, Nanchal R, Karvellas CJ. Pathophysiology of acute liver failure. Nutr Clin Pract 2020; 35: 24–29.

15 Possamai LA, Thursz MR, Wendon JA, Antoniades CG. Modulation of monocyte/macrophage function: a therapeutic strategy in the treatment of acute liver failure. J Hepatol 2014; 61: 439–45.

16 Rolando N, Wade J, Davalos M, Wendon J, Philpott-Howard J, Williams R. The systemic inflammatory response syndrome in acute liver failure. Hepatology 2000; 32: 734–39.

17 Stravitz RT, Kramer DJ. Management of acute liver failure. Nat Rev Gastroenterol Hepatol 2009; 6: 542–53.

18 Richardson D, Bellamy M. Intracranial hypertension in acute liver failure. Nephrol Dial Transplant 2002; 17: 23–27.

19 Lutfi R, Abulebda K, Nitu ME, Molleston JP, Bozic MA, Subbarao G. Intensive care management of pediatric acute liver failure. J Pediatr Gastroenterol Nutr 2017; 64: 660–70.

20 Bulut Y, Sapru A, Roach GD. Hemostatic balance in pediatric acute liver failure: epidemiology of bleeding and thrombosis, physiology, and current strategies. Front Pediatr 2020; 8: 618119.

21 Berardi G, Tuckfield L, DelVecchio MT, Aronoff S. Differential diagnosis of acute liver failure in children: a systematic review. Pediatr Gastroenterol Hepatol Nutr 2020; 23: 501–10.

22 Rand EB, Karpen SJ, Kelly S, et al. Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin. J Pediatr 2009; 155: 566–71.

23 Jagadisan B, Dhawan A. Emergencies in paediatric hepatology. J Hepatol 2022; 76: 1199–214.

24 Chanpong A, Dhawan A. Re-evaluation of King’s Wilson Index in children with acutely decompensated hepatic Wilson disease. J Pediatr Gastroenterol Nutr 2021; 74: 510–15.

25 Marsh K, Tayler R, Pollock L, et al. Investigation into cases of hepatitis of unknown aetiology among young children, Scotland, 1 January 2022 to 12 April 2022. Euro Surveill 2022;

27: 2200318.

26 Deep A, Grammatikopoulos T, Heaton N, Verma A, Dhawan A. Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit. Intensive Care Med 2022; published online June 10. https://doi. org/10.1007/s00134-022-06765-3.

27 Hegarty R, Gibson P, Sambrotta M, et al. Study of acute liver failure in children using next generation sequencing technology. J Pediatr 2021; 236: 124–30.

28 Quadros J, Piedade C, Lopes MF. Auxiliary liver transplantation for management of acute liver failure in children—systematic review. Transplant Rev (Orlando) 2021; 35: 100631.

29 Dal-Secco D, Wang J, Zeng Z, et al. A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury. J Exp Med 2015; 212: 447–56.

30 Liew PX, Lee WY, Kubes P. iNKT Cells orchestrate a switch from inflammation to resolution of sterile liver injury. Immunity 2017; 47: 752–765.e5.

31 Strey CW, Markiewski M, Mastellos D, et al. The proinflammatory mediators C3a and C5a are essential for liver regeneration. J Exp Med 2003; 198: 913–23.

32 Antoniades CG, Berry PA, Wendon JA, Vergani D. The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol 2008; 49: 845–61.

33 Rolando N, Philpott-Howard J, Williams R. Bacterial and fungal infection in acute liver failure. Semin Liver Dis 1996; 16: 389–402.

34 Godbole G, Shanmugam N, Dhawan A, Verma A. Infectious complications in pediatric acute liver failure. J Pediatr Gastroenterol Nutr 2011; 53: 320–25.

35 Deep A, Stewart CE, Dhawan A, Douiri A. Effect of continuous renal replacement therapy on outcome in pediatric acute liver failure. Crit Care Med 2016; 44: 1910–19.

36 Raghunathan V, Dhaliwal M, Karkra S, Mohan N. Prevalence of acute kidney injury network (AKIN) in pediatric non-acetaminophen acute liver failure (pNA-ALF) and addition of akin staging to King’s College Criteria (KCC) in pNA-ALF improves prognostic value. J Clin Exp Hepatol 2015; 5: S8.

37 Raina R, Bedoyan JK, Lichter-Konecki U, et al. Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy. Nat Rev Nephrol 2020; 16: 471–82.

38 Chevret L, Durand P, Lambert J, et al. High-volume hemofiltration in children with acute liver failure*. Pediatr Crit Care Med 2014; 15: e300–05.

39 Slack AJ, Auzinger G, Willars C, et al. Ammonia clearance with haemofiltration in adults with liver disease. Liver Int 2014; 34: 42–48.

 

Comentarios

Para ver los comentarios de sus colegas o para expresar su opinión debe ingresar con su cuenta de IntraMed.

AAIP RNBD
Términos y condiciones de uso | Política de privacidad | Todos los derechos reservados | Copyright 1997-2024