Estudio TIRTLE el cual nos habla sobre el uso de Tirzepatidese enc en Diabetes Tipo 1 ¿Qué se encontró? ¿Qué hubo de relevante en este estudio?
En pacientes con diabetes tipo 1 y obesidad tras 12 semanas de uso de Tirzepatide vs placebo se encontró:
- Disminución de Peso en 8.7Kg (Equivalente a 8.8% del peso corporal total )
- Disminución de HbA1c en 0.4%
- Reducción de Dosis Total Diaria en un 35.1%
- Reducción de Dosis de bolos de insulina en un 49%
- Reducción de Insulina Basal en un 25%
Grandes beneficios , ¿Cuáles son las preguntas que quedan por responder? ¿Es realmente una opción sostenible a largo plazo, tanto economicamente , como en efectos adversos y beneficios para el paciente ?
Jennifer R. Snaith, Ruth Frampton, Dorit Samocha-Bonet, Jerry R. Greenfield; Tirzepatide in Adults With Type 1 Diabetes: A Phase 2 Randomized Placebo-Controlled Clinical Trial. Diabetes Care 2 January 2026; 49 (1): 161–170. https://doi.org/10.2337/dc25-2379
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