Perfiles de respuesta inmune para SARS-CoV2 según la edad

1. World Health Organization. WHO coronavirus disease (COVID-19) dashboard. Accessed January 31, 2021.

 https:// covid19.who.int/?gclid=CjwKCAiAtK79BRAIEiwA4OskBtAbOw6T6wNgUS76dyazGbUP3AdVbHz7JZLTG4xKNRk_ r3W9C9NQ-xoCRDoQAvD_BwE 2. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention.JAMA. 2020;323(13):1239-1242. doi:10.1001/jama.2020.2648

3. Centers for Disease Control and Prevention. Demographic trends of COVID-19 cases and deaths in the US reported to CDC. Data retrieved July 27, 2020. https://www.cdc.gov/covid-data-tracker/index. html#demographics

4. Leeb RT, Price S, Sliwa S, et al. COVID-19 trends among school-aged children—United States, March 1-September 19, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(39):1410-1415. doi:10.15585/mmwr.mm6939e2

5. Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020;109(6):1088-1095. doi:10.1111/apa.15270

6. Laws RL, Chancey RJ, Rabold EM, et al. Symptoms and transmission of SARS-CoV-2 among children—Utah and Wisconsin, March-May 2020. Pediatrics. 2021;147(1):e2020027268. doi:10.1542/peds.2020-027268

7. Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145(6): e20200702. doi:10.1542/peds.2020-0702

8. Elahi S. Neonatal and children’s immune system and COVID-19: biased immune tolerance versus resistance strategy. J Immunol. 2020;205(8):1990-1997. doi:10.4049/jimmunol.2000710 9. Zimmermann P, Curtis N. Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children. Pediatr Infect Dis J. 2020; 39(5):355-368. doi:10.1097/INF.0000000000002660

10. Feldstein LR, Rose EB, Horwitz SM, et al; Overcoming COVID-19 Investigators; CDC COVID-19 Response Team. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med. 2020;383(4):334-346. doi: 10.1056/NEJMoa2021680

11. Whittaker E, Bamford A, Kenny J, et al; PIMS-TS Study Group and EUCLIDS and PERFORM Consortia. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2.JAMA. 2020;324(3):259-269. doi:10.1001/jama.2020.10369

12. Weisberg SP, Connors TJ, Zhu Y, et al. Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum. Nat Immunol. 2021;22(1):25-31. doi:10.1038/s41590-020-00826-9

13. Lee PI, Hu YL, Chen PY, Huang YC, Hsueh PR. Are children less susceptible to COVID-19? J Microbiol Immunol Infect. 2020;53(3):371-372. doi:10.1016/j.jmii.2020.02.011