Los mecanismos biológicos adaptativos que "defienden" el peso | 13 ABR 15

¿Por qué es tan difícil bajar de peso?

Las estrategias para el descenso de peso deben considerar los mecanismos biológicos que se oponen a ello.
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Autor/a: Christopher N Ochneremail , Adam G Tsai , Robert F Kushner , Thomas A Wadden Fuente: The Lancet Diabestes & Endocrinology Volume 3, No. 4, p232–234, April 2015 DOI: http://dx.doi.org/10.1016/S2213-8587(15)00009-1 Treating obesity seriously: when recommendations for lifestyle change confront biological adaptations
INDICE:  1. Desarrollo | 2. Referencias
Referencias
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  5. Rosenbaum, M and Leibel, RL. Adaptive thermogenesis in humans. Int J Obes. 2010; 34: S47–S55
  6. Rosenbaum, M and Leibel, RL. 20 years of leptin: role of leptin in energy homeostasis in humans. J Endocrinol. 2014; 223: T83–T96
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  8. Gadde, KM, Allison, DB, Ryan, DH et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011; 377: 1341–1352
  9. Wadden, TA, Berkowitz, RI, Womble, LG et al. Randomized trial of lifestyle modification and pharmacotherapy for obesity. N Engl J Med. 2005; 353: 2111–2120
  10. Sjöström, L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013; 273: 219–234
  11. Le Roux, CW, Welbourn, R, Werling, M et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg. 2007; 246: 780–785
  12. Ochner, CN, Kwok, Y, Conceicao, E et al. Selective reduction in neural responses to high calorie foods following gastric bypass surgery. Ann Surg. 2011; 253: 502–507
  13. Jensen, MD, Ryan, DH, Donato, KA et al. Guidelines (2013) for managing overweight and obesity in adults. Obesity. 2014; 22: S1–410
  14. MacLean, PS, Wing, RR, Davidson, T et al. NIH working group report: innovative research to improve maintenance of weight loss. Obesity. 2015; 23: 7–15
 

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