Investigación y manejo | 06 MAR 23

Incidentalomas pancreáticos

Si bien son relativamente poco comunes, los incidentalomas de páncreas (IP) se asocian con una tasa elevada de malignidad potencial en comparación con su ubicación en otros órganos.
Autor/a: Marco Del Chiaro, Robert J. Torphy, Richard D. Schulick Journal of Internal Medicine, 2021, 290; 969979.
INDICE:  1. Texto principal | 2. Referencias bibliográficas
Referencias bibliográficas

1 Rosenkrantz AB, Hanna TN, Babb JS, Duszak R Jr. Changes in emergency department imaging: perspectives from National Patient Surveys over two decades. J Am Coll

Radiol. 2017;14(10):1282–90.

2 Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, et al. The prevalence of pituitary adenomas. Cancer 2004;101(3):613–9.

3 Kwan JL, Yermak D, Markell L, Paul NS, Shojania KG, Cram P. Follow up of incidental high-risk pulmonary nodules on computed tomography pulmonary angiography at care transitions. J Hosp Med. 2019;14(6):349–52.

4 Ravine D, Gibson RN, Donlan J, Sheffield LJ. An ultrasound renal cyst prevalence survey: specificity data for inherited renal cystic diseases. Am J Kidney Dis. 1993;22(6):803–7.

5 Stang MT, Carty SE. Recent developments in predicting thyroid malignancy. Curr Opin Oncol. 2009;21(1):11–7.

6 Tosaka A, Ohya K, Yamada K, Ohashi H, Kitahara S, Sekine H, et al. Incidence and properties of renal masses and asymptomatic renal cell carcinoma detected by abdominal ultrasonography. J Urol. 1990;144(5):1097–9.

7 Hitzeman N, Cotton E. Incidentalomas: initial management. Am Fam Physician. 2014;90(11):784–9.

8 Berland LL, Silverman SG, Gore RM, Mayo-Smith WW, Megibow AJ, Yee J, et al. Managing incidental findings on abdominal CT: white paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2010;7(10):754–73.

9 Ehrl D, Rothaug K, Herzog P, Hofer B, Rau H-G. Incidentaloma of the liver: management of a diagnostic and therapeutic dilemma. HPB Surg. 2012;2012:891787.

10 Bovio S, Cataldi A, Reimondo G, Sperone P, Novello S, Berruti A, et al. Prevalence of adrenal incidentaloma in a contemporary computerized tomography series. J Endocrinol Invest. 2006;29(4):298–302.

11 Lee KS, Sekhar A, Rofsky NM, Pedrosa I. Prevalence of incidenta pancreatic cysts in the adult population on MR imaging. Am J Gastroenterol. 2010;105(9):2079–84.

12 Fernández-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003;138(4):427–3; discusión 33–4.

13 Del Chiaro M, Segersvard R, Lohr M, Verbeke C. Early detection and prevention of pancreatic cancer: is it really posible today? World J Gastroenterol. 2014;20(34):12118–31.

14 Bouquot M, Gaujoux S, Cauchy F, Birnbaum D, Dokmak S, Levy P, et al. Pancreatectomy for pancreatic incidentaloma: what are the risks?. Pancreatology 2018;18(1):114–21.

15 Winter JM, Cameron JL, Lillemoe KD, Campbell KA, Chang D, Riall TS, et al. Periampullary and pancreatic incidentaloma: a single institution’s experience with an increasingly Common diagnosis. Ann Surg. 2006;243(5):673–80; discussion 80–3.

16 Lahat G, Ben Haim M, Nachmany I, Sever R, Blachar A, Nakache R, et al. Pancreatic incidentalomas: high rate of potentially malignant tumors. J Am Coll Surg. 2009;209(3):313–9.

17 Sachs T, Pratt WB, Callery MP, Vollmer CM Jr. The incidental asymptomatic pancreatic lesion: nuisance or threat? J. Gastrointest Surg. 2009;13(3):405–15.

18 Bruzoni M, Johnston E, Sasson AR. Pancreatic incidentalomas: clinical and pathologic spectrum. Am J Surg. 2008;195(3):329–32; discussion 32.

19 Kromrey ML, Bulow R, Hubner J, Paperlein C, Lerch MM, Ittermann T, et al. Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study. Gut 2018;67(1): 138–45.

20 European Study Group on Cystic Tumors of the Pancreas, Del Chiaro Marco, Besselink Marc G, Scholten Lianne, Bruno Marco J, Cahen Djuna L. European evidence-based guidelines on pancreatic cystic neoplasms. Gut 2018;67(5): 789–804.

21 Del Chiaro M, Verbeke C, Salvia R, Kloppel G, Werner J, McKay C, et al. European experts consensus statement on cystic tumours of the pancreas. Dig Liver Dis. 2013;45(9):703–11.

22 Jais B, Rebours V, Malleo G, Salvia R, Fontana M, Maggino L, et al. Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas). Gut 2016;65(2):305–12.

23 van Huijgevoort NCM, Del Chiaro M, Wolfgang CL, van Hooft JE, Besselink MG. Diagnosis and management of pancreatic cystic neoplasms: current evidence and guidelines. Nat Rev Gastroenterol Hepatol. 2019;16(11):676–89.

24 Salvia R, Malleo G, Marchegiani G, Pennacchio S, Paiella S, Paini M, et al. Pancreatic resections for cystic neoplasms: from the surgeon’s presumption to the pathologist’s reality. Surgery 2012;152(3 Suppl 1):S135–42.

25 Del Chiaro M, Segersvärd R, Pozzi Mucelli R, Rangelova E, Kartalis N, Ansorge C, et al. Comparison of preoperative conference-based diagnosis with histology of cystic tumors of the pancreas. Ann Surg Oncol. 2014;21(5):1539–44.

26 Correa-Gallego C, Ferrone CR, Thayer SP, Wargo JA, Warshaw AL, Fernandez-Del Castillo C. Incidental pancreatic cysts: do we really know what we are watching? Pancreatology 2010;10(2-3):144–50.

27 Gaiser RA, Halimi A, Alkharaan H, Lu L, Davanian H, Healy K, et al. Enrichment of oral microbiota in early cystic precursors to invasive pancreatic cancer. Gut 2019;68(12):2186– 94.

28 Gaiser RA, Pessia A, Ateeb Z, Davanian H, Fernández Moro C, Alkharaan H, et al. Integrated targeted metabolomic and lipidomic analysis: a novel approach to classifying early cystic precursors to invasive pancreatic cancer. Sci Rep. 2019;9(1):10208.

29 Wu YHA, Samuels JM, Harnke B, Negrini D, Al-Musawi MH, Meguid C, et al. Multifocal/diffuse pancreatic serous cystic neoplasms: systematic review with a new case. Pancreatology 2020;20(5):902–9.

30 Tanaka M, Chari S, Adsay V, Fernandez-del Castillo C, Falconi M, Shimizu M, et al. International consensus guidelines formanagement of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology 2006;6(1-2):17–32.

31 Del ChiaroM, Beckman R, Ateeb Z, Orsini N, Rezaee N, Manos L, et al. Main duct dilatation is the best predictor of highgrade dysplasia or invasion in intraductal papillary mucinous neo of the literature. Pancreatology 2016;16(6):1028–36.



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