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Trombosis venosa profunda y embolia pulmonar

Epidemiología, diagnóstico y tratamiento de la trombosis venosa profunda de las piernas y de la embolia pulmonar.
Autor/a: Marcello Di Nisio, Nick van Es, Harry R Büller Deep vein thrombosis and pulmonary embolism
INDICE:  1. Página 1 | 2. Página 1
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1 Raskob GE, Angchaisuksiri P, Blanco AN, et al. Thrombosis: a major contributor to global disease burden. Arterioscler Thromb Vasc Biol 2014; 34: 2363–71.

2 Cohen AT, Agnelli G, Anderson FA, et al. Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality. Thromb Haemost 2007; 98: 756–64.

3 Grosse SD, Nelson RE, Nyarko KA, Richardson LC, Raskob GE. The economic burden of incident venous thromboembolism in the United States: a review of estimated attributable healthcare costs. Thromb Res 2016; 137: 3–10.

4 Huang W, Goldberg RJ, Anderson FA, Kiefe CI, Spencer FA. Secular trends in occurrence of acute venous thromboembolism: the Worcester VTE study (1985–2009). Am J Med 2014;127: 829–39.e5.

5 Jensvoll H, Severinsen MT, Hammerstrom J, et al. Existing data sources in clinical epidemiology: the Scandinavian Thrombosis and Cancer Cohort. Clin Epidemiol 2015; 7: 401–10.

6 Heit JA. Epidemiology of venous thromboembolism. Nat Rev Cardiol 2015; 12: 464–74.

7 Bell EJ, Lutsey PL, Basu S, et al. Lifetime risk of venous thromboembolism in two cohort studies. Am J Med 2016;129: 339.e19–339.e26.

8 Deitelzweig SB, Lin J, Johnson BH, Schulman KL. Venous thromboembolism in the US: does race matter? J Thromb Thrombolysis 2011; 31: 133–38.

9 Roach REJ, Lijfering WM, Rosendaal FR, Cannegieter SC, Le Cessie S. Sex diff erence in risk of second but not of fi rst venous thrombosis: paradox explained. Circulation 2014; 129: 51–56.

10 Sogaard KK, Schmidt M, Pedersen L, Horvath-Puho E, Sorensen HT. 30-year mortality after venous thromboembolism:a population-based cohort study. Circulation 2014; 130: 829–36.

11 Stein PD, Matta F, Alrifai A, Rahman A. Trends in case fatality rate in pulmonary embolism according to stability and treatment. Thromb Res 2012; 130: 1–6.

12 Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 1999; 353: 1386–89.

13 Kearon C. Natural history of venous thromboembolism. Circulation 2003; 107: I22–30.

14 Kahn SR, Comerota AJ, Cushman M, et al. The postthrombotic syndrome: evidence-based prevention, diagnosis, and treatment strategies. Circulation 2014; 130: 1636–61.

15 Hoeper MM, Madani MM, Nakanishi N, Meyer B, Cebotari S, Rubin LJ. Chronic thromboembolic pulmonary hypertension. Lancet Respir Med 2014; 2: 573–82.

16 Kearon C, Ageno W, Cannegieters SC, Cosmi B, Geersing G-J, Kyrle PA, for The subcommittees on Control of Anticoagulation and Predictive and Diagnostic Variables in Thrombotic Disease. Categorization of patients as having provoked or unprovoked VTE: guidance from the SSC of ISTH. J Thromb Haemost 2016; 14: 1–4.

17 Rosendaal FR. Venous thrombosis: a multicausal disease. Lancet 1999; 353: 1167–73.

18 Januel J-M, Chen G, Ruffi eux C, et al. Symptomatic in-hospital deep vein thrombosis and pulmonary embolism following hip and knee arthroplasty among patients receiving recommended prophylaxis: a systematic review. JAMA 2012; 307: 294–303.

19 Timp JF, Braekkan SK, Versteeg HH, Cannegieter SC. Epidemiology of cancer-associated venous thrombosis. Blood 2013; 122: 1712–23.

20 MacCallum P, Bowles L, Keeling D. Diagnosis and management of heritable thrombophilias. BMJ 2014; 349: g4387–g4387.

21 Morange P-E, Suchon P, Tregouet D-A. Genetics of venous thrombosis: update in 2015. Thromb Haemost 2015; 114: 910–19.

22 Stein PD, Matta F, Musani MH, Diaczok B. Silent pulmonary embolism in patients with deep venous thrombosis: a systematic review. Am J Med 2010; 123: 426–31.

23 Pollack C V, Schreiber D, Goldhaber SZ, et al. Clinical characteristics, management, and outcomes of patients diagnosed with acute pulmonary embolism in the emergency department: initial report of EMPEROR (Multicenter Emergency Medicine Pulmonary Embolism in the Real World Registry). J Am Coll Cardiol2011; 57: 700–06.

24 Ceriani E, Combescure C, Le Gal G, et al. Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysis. J Thromb Haemost 2010; 8: 957–70.

25 Lucassen W, Geersing GJ, Erkens PMG, et al. Clinical decision rules for excluding pulmonary embolism: a meta-analysis. Ann Intern Med 2011; 155: 448–60.

26 Geersing GJ, Zuithoff NPA, Kearon C, et al. Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. BMJ 2014; 348: g1340.

27 Wells PS, Anderson DR, Rodger M, et al. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med 2003; 349: 1227–35.

28 Wells PS, Anderson DR, Rodger M, et al. Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 2000; 83: 416–20.

29 Gibson NS, Sohne M, Kruip MJ, et al. Further validation and simplifi cation of the Wells clinical decision rule in pulmonary embolism. Thromb Haemost 2008; 99: 229–34.

30 Le Gal G, Righini M, Roy P-M, et al. Prediction of pulmonary embolism in the emergency department: the revised Geneva score. Ann Intern Med 2006; 144: 165–71.

31 Klok FA, Mos ICM, Nijkeuter M, et al. Simplifi cation of the revised Geneva score for assessing clinical probability of pulmonary embolism. Arch Intern Med 2008; 168: 2131–36.

32 Wells PS, Anderson DR, Bormanis J, et al. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 1997; 350: 1795–98.

33 Righini M, Van Es J, Den Exter PL, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study. JAMA 2014; 311: 1117–24.

34 Douma RA, Mos ICM, Erkens PMG, et al. Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study. Ann Intern Med 2011;154: 709–18.

35 van Belle A, Buller HR, Huisman M V, et al. Eff ectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 2006; 295:172–79.

36 Di Nisio M, Squizzato A, Rutjes AWS, Buller HR, Zwinderman AH, Bossuyt PMM. Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic review. J Thromb Haemost 2007; 5: 296–304.

37 Geersing GJ, Janssen KJM, Oudega R, et al. Excluding venous thromboembolism using point of care D-dimer tests in outpatients: a diagnostic meta-analysis. BMJ 2009; 339: b2990.

38 Buller HR, Ten Cate-Hoek AJ, Hoes AW, et al. Safely ruling out deep venous thrombosis in primary care. Ann Intern Med 2009;150: 229–35.

39 Wells PS, Anderson DR, Rodger M, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med 2001; 135: 98–107.

40 Silveira PC, Ip IK, Goldhaber SZ, Piazza G, Benson CB, Khorasani R. Performance of Wells score for deep vein thrombosis in the inpatient setting. JAMA Intern Med 2015; 175: 1112–17.

41 Douma RA, van Sluis GL, Kamphuisen PW, et al. Clinical decision rule and D-dimer have lower clinical utility to exclude pulmonary embolism in cancer patients. Explanations and potential ameliorations. Thromb Haemost 2010; 104: 831–36.

42 Raja AS, Greenberg JO, Qaseem A, et al. Evaluation of patients with suspected acute pulmonary embolism: best practice advice from the Clinical Guidelines Committee of the American College of Physicians. Ann Intern Med 2015; 163: 701–11.

43 Mos ICM, Douma RA, Erkens PMG, et al. Diagnostic outcome management study in patients with clinically suspected recurrent acute pulmonary embolism with a structured algorithm. Thromb Res 2014; 133: 1039–44.

44 van Es N, van der Hulle T, van Es J, et al. Wells rule and D-dimer testing to rule out pulmonary embolism: a systematic review and individual-patient data meta-analysis. Ann Intern Med 2016;published online May 17. DOI:10.7326/M16-0031.

45 Chan W, Lee AY, Spencer FA, et al. Predicting deep venous thrombosis in pregnancy: out in ‘LEFt’ fi eld? Ann Intern Med 2009; 151: 85–92.

46 Douma RA, le Gal G, Sohne M, et al. Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts. BMJ 2010; 340: c1475.

47 Schouten HJ, Geersing GJ, Koek HL, et al. Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis. BMJ 2013; 346: f2492.

48 Penaloza A, Roy PM, Kline J, et al. Performance of age-adjusted D-dimer cut-off to rule out pulmonary embolism. J Thromb Haemost 2012; 10: 1291–96.

49 Singh B, Mommer SK, Erwin PJ, Mascarenhas SS, Parsaik AK. Pulmonary embolism rule-out criteria (PERC) in pulmonary embolism--revisited: a systematic review and meta-analysis. Emerg Med J 2013; 30: 701–06.

50 Hugli O, Righini M, Le Gal G, et al. The pulmonary embolism rule-out criteria (PERC) rule does not safely exclude pulmonary embolism. J Thromb Haemost 2011; 9: 300–04.

51 Perrier A, Nendaz MR, Sarasin FP, Howarth N, Bounameaux H. Cost-eff ectiveness analysis of diagnostic strategies for suspected pulmonary embolism including helical computed tomography. Am J Respir Crit Care Med 2003; 167:39–44.

52 Roy P-M, Meyer G, Vielle B, et al. Appropriateness of diagnostic management and outcomes of suspected pulmonary embolism. Ann Intern Med 2006; 144: 157–64.

53 Runyon MS, Richman PB, Kline JA. Emergency medicine practitioner knowledge and use of decision rules for the evaluation of patients with suspected pulmonary embolism: variations by practice setting and training level. Acad Emerg Med 2007; 14: 53–57.

54 Bates SM, Jaeschke R, Stevens SM, et al. Diagnosis of DVT: antithrombotic therapy and prevention of thrombosis, 9th edn. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141: e351S–418S.

55 Johnson SA, Stevens SM, Woller SC, et al. Risk of deep vein thrombosis following a single negative whole-leg compression ultrasound: a systematic review and meta-analysis. JAMA 2010;303: 438–45.

56 Bernardi E, Camporese G, Buller HR, et al. Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: a randomized controlled trial. JAMA 2008; 300: 1653–59.

57 Righini M, Paris S, Le Gal G, Laroche J-P, Perrier A, Bounameaux H. Clinical relevance of distal deep vein thrombosis. Review of literature data. Thromb Haemost 2006; 95: 56–64.

58 Cogo A, Lensing AW, Koopman MM, et al. Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study. BMJ 1998; 316: 17–20.

59 Elias A, Mallard L, Elias M, et al. A single complete ultrasound investigation of the venous network for the diagnostic management of patients with a clinically suspected fi rst episode of deep venous thrombosis of the lower limbs. Thromb Haemost 2003;89: 221–27.

60 Birdwell BG, Raskob GE, Whitsett TL, et al. The clinical validity of normal compression ultrasonography in outpatients suspected of having deep venous thrombosis. Ann Intern Med 1998; 128: 1–7.

61 Schellong SM, Schwarz T, Halbritter K, et al. Complete compression ultrasonography of the leg veins as a single test for the diagnosis of deep vein thrombosis. Thromb Haemost 2003; 89: 228–34.

Schwarz T, Schmidt B, Schmidt B, Schellong SM. Interobserver agreement of complete compression ultrasound for clinically suspected deep vein thrombosis. Clin Appl Thromb 2002; 8: 45–49.

63 Camporese G, Bernardi E, Scarano L, et al. Outcome of patients with suspected lower limb symptomatic deep vein thrombosis and a normal ultrasound-based initial diagnostic workup: a prospective study. J Thromb Haemost 2012; 10: 2605–06.

64 Palareti G. How I treat isolated distal deep vein thrombosis (IDDVT). Blood 2014; 123: 1802–09.

65 Kearon C, Ginsberg JS, Hirsh J. The role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism. Ann Intern Med 1998; 129: 1044–49.

66 Wells PS, Owen C, Doucette S, Fergusson D, Tran H. Does this patient have deep vein thrombosis? JAMA 2006; 295: 199–207.

67 Kraaijenhagen RA, Piovella F, Bernardi E, et al. Simplifi cation of the diagnostic management of  suspected deep vein thrombosis. Arch Intern Med 2002; 162: 907–11.

68 Ageno W, Camporese G, Riva N, et al, for the PALLADIO study investigators. Analysis of an algorithm incorporating limited and whole-leg assessment of the deep venous system in symptomatic outpatients with suspected deep-vein thrombosis (PALLADIO): a prospective, multicentre, cohort study. Lancet Haematol 2015;2: e474–80.

69 Liu D, Peterson E, Dooner J, et al. Diagnosis and management of iliofemoral deep vein thrombosis: clinical practice guideline. CMAJ 2015; 187: 1288–96.

70 Linkins L-A, Stretton R, Probyn L, Kearon C. Interobserver agreement on ultrasound measurements of residual vein diameter, thrombus echogenicity and Doppler venous fl ow in patients with previous venous thrombosis. Thromb Res 2006; 117: 241–47.

71 Tan M, Mol GC, van Rooden CJ, et al. Magnetic resonance direct thrombus imaging diff erentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis. Blood 2014; 124: 623–27.

72 Van Beek EJR, Brouwers EMJ, Song BIN, Stein PD, Oudkerk M. Clinical validity of a normal pulmonary angiogram in patients with suspected pulmonary embolism—a critical review. Clin Radiol 2001;56: 838–42.

73 Moores LK, Jackson WL, Shorr AF, Jackson JL. Meta-analysis: outcomes in patients with suspected pulmonary embolism managed with computed tomographic pulmonary angiography. Ann Intern Med 2004; 141: 866–74.

74 PIOPED Investigators. Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). JAMA 1990;263: 2753–59.

75 Huisman M V., Klok FA. Diagnostic management of clinically suspected acute pulmonary embolism. J Thromb Haemost 2009; 7: 312–17.

76 Carrier M, Righini M, Le Gal G. Symptomatic subsegmental pulmonary embolism: what is the next step? J Thromb Haemost 2012; 10: 1486–90.

77 Righini M, Le Gal G, Aujesky D, et al. Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trial. Lancet 2008; 371: 1343–52.

78 Anderson DR, Kahn SR, Rodger MA, et al. Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial. JAMA 2007; 298: 2743–53.

79 Konstantinides S V, Torbicki A, Agnelli G, et al. 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J 2014; 35: 3033–69.

80 Ageno W, Squizzato A, Wells PS, Buller HR, Johnson G. The diagnosis of symptomatic recurrent pulmonary embolism and deep vein thrombosis: guidance from the SSC of the ISTH. J Thromb Haemost 2013; 11: 1597–602.

 

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