Revisión | 10 FEB 14

Osteomielitis aguda en niños

A pesar de que esta patología en los niños se diagnostique y se trate apropiadamente puede ser una enfermedad devastadora o fatal. Esta revisión resume su tratamiento en la actualidad.
Autor/a: Dres. Heikki Peltola, MD, y Markus Pääkkönen, MD N Engl J Med 2014; 370:352-360 DOI: 10.1056/NEJMra1213956
INDICE:  1.  | 2. Referencias
Referencias

1 Krogstad P. Osteomyelitis. In: Feigin RD, Cherry JD, Demmler-Harrison GJ, Kaplan SL, eds. Pediatric infectious diseases. 6th ed. Philadelphia: Saunders, 2009:725-42.

.

2 Riise OR, Kirkhus E, Handeland KS, et al. Childhood osteomyelitis-incidence and differentiation from other acute onset musculoskeletal features in a population-based study. BMC Pediatr 2008;8:45-45
CrossRef | Medline
.

3 Grammatico-Guillon L, Maakaroun Vermesse Z, Baron S, Gettner S, Rusch E, Bernard L. Paediatric bone and joint infections are more common in boys and toddlers: a national epidemiology study. Acta Paediatr 2013;102:e120-e125
CrossRef | Web of Science | Medline


4- Gillespie WJ, Mayo KM. The management of acute haematogenous osteomyelitis in the antibiotic era: a study of the outcome. J Bone Joint Surg Br 1981;63:126-131
Web of Science | Medline


5 Syrogiannopoulos GA, Nelson JD. Duration of antimicrobial therapy for acute suppurative osteoarticular infections. Lancet 1988;1:37-40
CrossRef | Web of Science | Medline


6 Jaberi FM, Shahcheraghi GH, Ahadzadeh M. Short-term intravenous antibiotic treatment of acute hematogenous bone and joint infection in children: a prospective randomized trial. J Pediatr Orthop 2002;22:317-320
Web of Science | Medline
.

7 Prado SMA, Lizama CM, Pena DA, Valenzuela MC, Viviani ST. Short duration of initial intravenous treatment in 70 pediatric patients with osteoarticular infections. Rev Chilena Infectol 2008;25:30-36
Web of Science | Medline
.

8 Jagodzinski NA, Kanwar R, Graham K, Bache CE. Prospective evaluation of a shortened regimen of treatment for acute osteomyelitis and septic arthritis in children. J Pediatr Orthop 2009;29:518-525
CrossRef | Web of Science | Medline
.

9 Peltola H, Paakkonen M, Kallio P, Kallio MJ. Short- versus long-term antimicrobial treatment for acute hematogenous osteomyelitis of childhood: prospective, randomized trial on 131 culture-positive cases. Pediatr Infect Dis J 2010;29:1123-1128
CrossRef | Web of Science | Medline
.

10 Atkins BL, Price EH, Tillyer L, Novelli V, Evans J. Salmonella osteomyelitis in sickle cell disease children in the east end of London. J Infect 1997;34:133-138
CrossRef | Web of Science | Medline
.

11 Yagupsky P, Porsch E, St Geme JW III. Kingella kingae: an emerging pathogen in young children. Pediatrics 2011;127:557-565
CrossRef | Web of Science | Medline
.

12 Dartnell J, Ramachandran M, Katchburian M. Haematogenous acute and subacute paediatric osteomyelitis: a systematic review of the literature. J Bone Joint Surg Br 2012;94:584-595
CrossRef | Medline
.

13 Ju KL, Zurakowski D, Kocher MS. Differentiating between methicillin-resistant and methicillin-sensitive Staphylococcus aureus osteomyelitis in children: an evidence-based clinical prediction algorithm. J Bone Joint Surg Am 2011;93:1693-1701
CrossRef | Medline
.

14 Liu C, Bayer A, Cosgrove SE, et al. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis 2011;52:e18-e55[Erratum, Clin Infect Dis 2011;53:319.]
CrossRef | Web of Science | Medline
.

15 Butbul-Aviel Y, Koren A, Halevy R, Sakran W. Procalcitonin as a diagnostic aid in osteomyelitis and septic arthritis. Pediatr Emerg Care 2005;21:828-832
CrossRef | Web of Science | Medline
.

16 Paakkonen M, Kallio MJ, Kallio PE, Peltola H. Sensitivity of erythrocyte sedimentation rate and C-reactive protein in childhood bone and joint infections. Clin Orthop Relat Res 2010;468:861-866
CrossRef | Web of Science | Medline
.

17 Arnold JC, Cannavino CR, Ross MK, et al. Acute bacterial osteoarticular infections: eight-year analysis of C-reactive protein for oral step-down therapy. Pediatrics 2012;130:e821-e828
CrossRef | Web of Science | Medline
.

18 Ceroni D, Regusci M, Pazos J, Dayer R, Kaelin A. Acute bone and joint infections in children: how much attention should be paid to persistent fever during intravenous antibiotic therapy? Rev Chir Orthop Reparatrice Appar Mot 2003;89:250-256
Web of Science | Medline
.

19 Connolly LP, Connolly SA, Drubach LA, Jaramillo D, Treves ST. Acute hematogenous osteomyelitis of children: assessment of skeletal scintigraphy-based diagnosis in the era of MRI. J Nucl Med 2002;43:1310-1316
Web of Science | Medline
.

20 Peltola H, Paakkonen M, Kallio P, Kallio MJT. Clindamycin vs. first-generation cephalosporins for acute osteoarticular infections of childhood -- a prospective quasi-randomized controlled trial. Clin Microbiol Infect 2012;18:582-589
CrossRef | Web of Science | Medline
.

21 Tetzlaff TR, Howard JB, McCraken GH, Calderon E, Larrondo J. Antibiotic concentrations in pus and bone of children with osteomyelitis. J Pediatr 1978;92:135-140
CrossRef | Web of Science | Medline
.

22 Feigin RD, Pickering LK, Anderson D, Keeney RE, Shackleford PG. Clindamycin treatment of osteomyelitis and septic arthritis in children. Pediatrics 1975;55:213-223
Web of Science | Medline
.

23 Landersdorfer CB, Bulitta JB, Kinzig M, Holzgrabe U, Sorgel F. Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations. Clin Pharmacokinet 2009;48:89-124
CrossRef | Medline
.

24 Kaplan SL, Afghani B, Lopez P, et al. Linezolid for the treatment of methicillin-resistant Staphylococcus aureus infection in children. Pediatr Infect Dis J 2003;22:Suppl:S178-S185
CrossRef | Medline
.

25 Chen CJ, Chiu CH, Lin TY, Lee ZL, Yang WE, Huang YC. Experience with linezolid therapy in children with osteoarticular infections. Pediatr Infect Dis J 2007;26:985-988
CrossRef | Web of Science | Medline
.

26 Summersgill JT, Schupp LG, Raff MJ. Comparative penetration of metronidazole, clindamycin, chloramphenicol, cefoxitin, ticarcillin, and moxalactam into bone. Antimicrob Agents Chemother 1982;21:601-603
CrossRef | Web of Science | Medline
.

27 Tetzlaff TR, McCracken GH Jr, Nelson JD. Oral antibiotic therapy for skeletal infections of children. II. Therapy of osteomyelitis and suppurative arthritis. J Pediatr 1978;92:485-490
CrossRef | Web of Science | Medline
.

28 Green JH. Cloxacillin in treatment of acute osteomyelitis. Br Med J 1967;2:414-416
CrossRef | Web of Science | Medline
.

29 Kaplan SL, Mason EO Jr, Feigin RD. Clindamycin versus nafcillin or methicillin in the treatment of Staphylococcus aureus osteomyelitis in children. South Med J 1982;75:138-142
CrossRef | Web of Science | Medline
.

30 Martinez-Aguilar G, Hammerman WA, Mason EO Jr, Kaplan SL. Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children. Pediatr Infect Dis J 2003;22:593-598
CrossRef | Web of Science | Medline
.

31 Dubnov-Raz G, Scheuerman O, Chodick G, Finkelstein Y, Samra Z, Garty BZ. Invasive Kingella kingae infections in children: clinical and laboratory characteristics. Pediatrics 2008;122:1305-1309
CrossRef | Web of Science | Medline
.

32 Messina AF, Namtu K, Guild M, Dumois JA, Berman DM. Trimethoprim-sulfamethoxazole therapy for children with acute osteomyelitis. Pediatr Infect Dis J 2011;30:1019-1021
CrossRef | Web of Science | Medline


33 Sherman JW, Conte JE Jr. Ceftriaxone treatment of multidrug-resistant Salmonella osteomyelitis. Am J Med 1987;83:137-138
CrossRef | Web of Science | Medline


34 Bradley JS, Jackson MA, Committee on Infectious Diseases, American Academy of Pediatrics. The use of systemic and topical fluoroquinolones. Pediatrics 2011;128:e1034-e1045
CrossRef | Web of Science | Medline
.

35 Ebong WW. Acute osteomyelitis in Nigerians with sickle cell disease. Ann Rheum Dis 1986;45:911-915
CrossRef | Web of Science | Medline

36 Mantadakis E, Plessa E, Vouloumanou EK, Michailidis L, Chatzimichael A, Falagas ME. Deep venous thrombosis in children with musculoskeletal infections: the clinical evidence. Int J Infect Dis 2012;16:e236-e243
CrossRef | Web of Science | Medline


37 Dich VQ, Nelson JD, Haltalin KC. Osteomyelitis in infants and children: a review of 163 cases. Am J Dis Child 1975;129:1273-1278
CrossRef | Web of Science | Medline


38 Vaughan PA, Newman NM, Rosman MA. Acute hematogenous osteomyelitis in children. J Pediatr Orthop 1987;7:652-655
Web of Science | Medline

39 Penberthy GC, Weller CN. Chemotherapy as an aid in the management of acute osteomyelitis. Ann Surg 1941;114:129-146
CrossRef | Medline
.

40 Kenney WE. The prognosis in acute haematogenous osteomyelitis with and without chemotherapy. Surgery 1944;16:477-484

.

41 Harris NH. Some problems in the diagnosis and treatment of acute osteomyelitis. J Bone Joint Surg Br 1960;42:535-541
Web of Science | Medline
.

42 Cole WG, Dalziel RE, Leitl S. Treatment of acute osteomyelitis in childhood. J Bone Joint Surg Br 1982;64:218-223
Web of Science | Medline
.

43 Bocchini CE, Hulten KG, Mason EO Jr, Gonzalez BE, Hammerman WA, Kaplan SL. Panton-Valentine leukocidin genes are associated with enhanced inflammatory response and local disease in acute hematogenous Staphylococcus aureus osteomyelitis in children. Pediatrics 2006;117:433-440
CrossRef | Web of Science | Medline
.

44 Belthur MV, Birchansky SB, Verdugo AA, et al. Pathologic fractures in children with acute Staphylococcus aureus osteomyelitis. J Bone Joint Surg Am 2012;94:34-42
CrossRef | Web of Science | Medline
.

45 Bradley JS, Kaplan SL, Tan TQ, et al. Pediatric pneumococcal bone and joint infections. Pediatrics 1998;102:1376-1382
CrossRef | Web of Science | Medline


46 Marti-Carvajal AJ, Agreda-Perez LH. Antibiotics for treating osteomyelitis in people with sickle cell disease. Cochrane Database Syst Rev 2012;12:CD007175-CD007175
Medline


47 Meller I, Manor Y, Bar-Ziv J, Torok G. Acute hematogenous osteomyelitis in children: long-term results of surgical treatment. Orthop Rev 1989;18:824-831
Medline
.

48 Connolly SA, Connolly LP, Drubach LA, Zurakowski D, Jaramillo D. MRI for detection of abscess in acute osteomyelitis of the pelvis in children. AJR Am J Roentgenol 2007;189:867-872
CrossRef | Web of Science | Medline
.

49 Vander Have KL, Karmazyn B, Verma M, et al. Community-associated methicillin-resistant Staphylococcus aureus in acute musculoskeletal infection in children: a game changer. J Pediatr Orthop 2009;29:927-931
CrossRef | Web of Science | Medline
.

50 Stephens MM, MacAuley P. Brodie's abscess: a long-term review. Clin Orthop Relat Res 1988;234:211-216
Web of Science | Medline
 

 

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